SCHEMBL7755873

SCHEMBL7755873

CC(Oc1ccccc1Cc1ccnn1C)N(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
ADRA2A P08913 8/20 0.37
ADRA2B P18089 8/20 0.37
ADRA2C P18825 8/20 0.37
HTR1A P08908 6/20 0.36
KCNH2 Q12809 3/20 0.34
ADRA1A P35348 1/20 0.32
FNTA P49354 1/20 0.31
FNTB P49356 1/20 0.31
PGR P06401 1/20 0.31
P2RX7 Q99572 1/20 0.31
DRD2 P14416 1/20 0.31
DRD1 P21728 1/20 0.31
DRD4 P21917 1/20 0.31
DRD5 P21918 1/20 0.31
IDH1 O75874 1/20 0.30
HRH1 P35367 1/20 0.30
KMT2A Q03164 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5599334 0.79 ADRB2 (0.35) MAOAMAOBADRA1AP2RX7DRD2
SCHEMBL6892797 0.76 DRD2 (0.58) DRD2DRD1DRD4DRD5HRH1
SCHEMBL10835682 0.74 MAOA (0.57) MAOAMAOBHTR1AADRA1ADRD2
Dimethylamine SCHEMBL7755880 0.74 THRB (0.44) P2RX7KMT2AL3MBTL1
Hydrochloric Acid SCHEMBL8856997 0.73 MAOA (0.56) MAOAMAOBHTR1AADRA1ADRD2
SCHEMBL6449575 0.69 P2RX7 (0.41) KCNH2PGRP2RX7KMT2A
SCHEMBL6651356 0.68 DRD2 (0.44) P2RX7DRD2DRD1DRD4DRD5
SCHEMBL27164556 0.66 CYP19A1 (0.44) PGRKMT2A
SCHEMBL7757122 0.65 KDM5A (0.43) KCNH2IDH1KMT2AL3MBTL1
SCHEMBL25217160 0.64 P2RX7 (0.38) KCNH2P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0808308-B1 METHOD FOR SEPARATING CARBINOLS ESTEVE LABOR DR (ES) 2001-03-07 EP disclosed
EP-0808308-A1 METHOD FOR SEPARATING CARBINOLS LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 1997-11-26 EP disclosed
WO-1997020817-A1 METHOD FOR SEPARATING CARBINOLS LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 1997-06-12 WO disclosed