Dimethylamine

Dimethylamine

SCHEMBL7755880

CCOc1ccccc1Cc1ccnn1C.CNC

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.44
LMNA P02545 2/20 0.44
L3MBTL1 Q9Y468 4/20 0.43
MAPT P10636 4/20 0.43
NPSR1 Q6W5P4 1/20 0.43
ATM Q13315 2/20 0.43
POLB P06746 1/20 0.43
CYP2D6 P10635 1/20 0.41
ALDH1A1 P00352 3/20 0.40
MEN1 O00255 1/20 0.40
GAA P10253 1/20 0.40
RECQL P46063 1/20 0.40
BLM P54132 1/20 0.40
KMT2A Q03164 1/20 0.40
PLEC Q15149 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
MAPK1 P28482 1/20 0.39
P2RX7 Q99572 1/20 0.38
HTR7 P34969 1/20 0.38
GRM5 P41594 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Citric Acid SCHEMBL8657221 0.84 LMNA (0.48) THRBLMNAL3MBTL1CYP2D6P2RX7
SCHEMBL6892797 0.80 DRD2 (0.58) LMNAALDH1A1HTR7
SCHEMBL5599334 0.77 ADRB2 (0.35) ALDH1A1P2RX7
SCHEMBL7755873 0.74 MAOA (0.40) L3MBTL1KMT2AP2RX7
SCHEMBL5254664 0.74 L3MBTL1 (0.64) THRBL3MBTL1MAPTNPSR1ATM
SCHEMBL6449575 0.72 P2RX7 (0.41) MAPTALDH1A1MEN1KMT2AP2RX7
SCHEMBL27164556 0.69 CYP19A1 (0.44) MAPTATMALDH1A1KMT2ATDP1
SCHEMBL19471246 0.69 P2RX7 (0.38) THRBLMNAL3MBTL1MAPTCYP2D6
SCHEMBL6651356 0.68 DRD2 (0.44) LMNAALDH1A1P2RX7HTR7
SCHEMBL7757122 0.68 KDM5A (0.43) LMNAL3MBTL1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0808308-B1 METHOD FOR SEPARATING CARBINOLS ESTEVE LABOR DR (ES) 2001-03-07 EP disclosed
US-5849931-A Process for separating carbinols LABORATORIOS DEL DR. ESTEVE S.A. (ES) 1998-12-15 US disclosed
EP-0808308-A1 METHOD FOR SEPARATING CARBINOLS LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 1997-11-26 EP disclosed
WO-1997020817-A1 METHOD FOR SEPARATING CARBINOLS LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 1997-06-12 WO disclosed