Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2694720 | 0.87 | — | — | |
| SCHEMBL17560322 | 0.73 | NOS1 (0.32) | DHFR | |
| SCHEMBL14843581 | 0.65 | DHFR (0.46) | DHFR | |
| SCHEMBL7753634 | 0.56 | NOS1 (0.44) | — | |
| SCHEMBL7757815 | 0.54 | NOS1 (0.43) | — | |
| SCHEMBL31315883 | 0.54 | NOS1 (0.43) | — | |
| SCHEMBL18020455 | 0.53 | DHFR (0.63) | DHFRLMNA | |
| SCHEMBL19206626 | 0.53 | NOS1 (0.34) | — | |
| SCHEMBL27409359 | 0.48 | TYMS (0.39) | — | |
| SCHEMBL30032784 | 0.48 | NOS1 (0.51) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001056385-A1 | METHODS AND COMPOSITIONS FOR ENHANCING FORMYLTETRAHYDROPTEROYLPOLYGLUTAMATE IN PLANTS | NONOMURA ARTHUR M (US) | 2001-08-09 | — | — | WO | claimed |
| US-6121195-A | STIMULATING CARBON FIXATION AND INCREASING THE GROWTH OF PLANTS BY ENHANCING THE AVAILABILITY OF C1-TETRAHYDROFOLATE IN THE LEAVES OF A PLANT | NONOMURA ARTHUR M (US) | 2000-09-19 | — | — | US | claimed |
| EP-0813510-A4 | METHODS AND COMPOSITIONS FOR ENHANCING FORMYLTETRAHYDROPTEROYLPOLYGLUTAMATE IN PLANTS | NONOMURA ARTHUR M (US) | 2000-07-26 | — | — | EP | claimed |
| EP-0813510-A1 | METHODS AND COMPOSITIONS FOR ENHANCING FORMYLTETRAHYDROPTEROYLPOLYGLUTAMATE IN PLANTS | NONOMURA, Arthur M. (US) | 1997-12-29 | — | — | EP | claimed |
| WO-1996027572-A1 | METHODS AND COMPOSITIONS FOR ENHANCING FORMYLTETRAHYDROPTEROYLPOLYGLUTAMATE IN PLANTS | NONOMURA ARTHUR M (US) | 1996-09-12 | — | — | WO | claimed |