Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.60 |
| ▸ | HTR1A | P08908 | 8/20 | 0.57 |
| ▸ | HTR2C | P28335 | 4/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9449688 | 0.93 | ADRA1D (0.61) | DRD2HTR1AHTR2CADRA1DADRA1A | |
| SCHEMBL7766463 | 0.89 | HTR7 (0.61) | DRD2DRD3 | |
| SCHEMBL7761410 | 0.84 | DRD2 (0.61) | DRD2HTR1AHTR2CDRD3ADRA1D | |
| SCHEMBL8787068 | 0.81 | HTR1A (0.58) | DRD2HTR1AHTR2CDRD3ADRA1D | |
| SCHEMBL8948173 | 0.80 | SIGMAR1 (0.46) | DRD2 | |
| SCHEMBL8948263 | 0.79 | SIGMAR1 (0.48) | DRD2HTR2C | |
| SCHEMBL9449863 | 0.78 | HTR1A (0.58) | DRD2HTR1AHTR2CDRD3 | |
| SCHEMBL7759833 | 0.78 | SIGMAR1 (0.51) | — | |
| SCHEMBL8786303 | 0.78 | ADRA1D (0.60) | DRD2HTR1AHTR2CADRA1DADRA1A | |
| SCHEMBL7759855 | 0.78 | CCR3 (0.58) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673934-B1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-04-25 | — | — | EP | disclosed |
| EP-0673934-A1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-27 | — | — | EP | disclosed |