Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.44 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | SLC25A20 | O43772 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8376547 | 0.99 | GPR84 (0.42) | CA2RECQLGPR84SLC25A20TP53 | |
| SCHEMBL478459 | 0.99 | GPR84 (0.42) | CA2RECQLGPR84SLC25A20TP53 | |
| Potassium Ion SCHEMBL11053756 | 0.97 | RECQL (0.43) | CA2RECQLGPR84SLC25A20TP53 | |
| SCHEMBL28190358 | 0.96 | RECQL (0.46) | CA2RECQLGPR84SLC25A20TP53 | |
| SCHEMBL8402079 | 0.92 | CA1 (0.38) | CA2RECQLGPR84SLC25A20TP53 | |
| SCHEMBL5965211 | 0.92 | RECQL (0.43) | CA2RECQLGPR84SLC25A20TP53 | |
| SCHEMBL16266427 | 0.90 | CA1 (0.38) | CA2RECQLGPR84SLC25A20TP53 | |
| SCHEMBL10798914 | 0.89 | RECQL (0.48) | CA2RECQLGPR84SLC25A20TP53 | |
| SCHEMBL9131227 | 0.89 | GPR84 (0.41) | CA2GPR84SLC25A20TP53CYP2D6 | |
| SCHEMBL478457 | 0.89 | GPR84 (0.41) | CA2GPR84SLC25A20TP53CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638705-B1 | ANCHOR BOLT FIXING CAPSULE | ASAHI CHEMICAL IND (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5544981-A | CASING HOLDS CURABLE RESIN, CURING AGENT AND SURFACTANT; ACTIVATED BY ACTION OF ANCHOR BOLT BEING DRIVEN INTO CAPSULE | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1996-08-13 | — | — | US | disclosed |
| EP-0638705-A1 | ANCHOR BOLT FIXING CAPSULE | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1995-02-15 | — | — | EP | disclosed |