Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.43 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.42 |
| ▸ | DUSP5 | Q16690 | 4/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.46 |
| ▸ | PKLR | P30613 | 4/20 | 0.46 |
| ▸ | PGAM1 | P18669 | 2/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | DUSP6 | Q16828 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL452424 | 0.89 | DUSP5 (0.50) | DUSP5PTPN1PKLRPGAM1PTGS1 | |
| SCHEMBL11199053 | 0.89 | DUSP5 (0.50) | DUSP5PTPN1PKLRPGAM1PTGS1 | |
| SCHEMBL169264 | 0.85 | ALDH1A1 (0.50) | DUSP5PTPN1PKLRPGAM1PTGS1 | |
| SCHEMBL9509844 | 0.84 | NR4A1 (0.50) | DUSP5PTPN1PKLRPGAM1PTGS1 | |
| SCHEMBL9805973 | 0.84 | PTGS1 (0.48) | DUSP5PTPN1PKLRPGAM1PTGS1 | |
| Lithium Ion SCHEMBL29083050 | 0.84 | DUSP5 (0.46) | DUSP5PTPN1PKLRPGAM1PTGS1 | |
| Potassium Ion SCHEMBL5191230 | 0.84 | NR4A1 (0.50) | DUSP5PTPN1PKLRPGAM1PTGS1 | |
| Water SCHEMBL28391333 | 0.82 | PTGS1 (0.47) | DUSP5PTPN1PKLRPGAM1PTGS1 | |
| Formaldehyde SCHEMBL5402512 | 0.82 | ALDH1A1 (0.46) | DUSP5PTPN1PKLRPGAM1PTGS1 | |
| Potassium Ion SCHEMBL6642207 | 0.81 | ALDH1A1 (0.50) | DUSP5PTPN1PKLRPGAM1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140731-A2 | POROUS CERAMIC MATRICES SUITABLE AS CATALYSTS SUPPORT | DYTECH CORPORATION LIMITED (GB) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000029353-A2 | POROUS CERAMIC MATRICES SUITABLE AS CATALYSTS SUPPORT | DYTECH CORPORATION LIMITED (GB) | 2000-05-25 | — | — | WO | disclosed |
| EP-0250219-B1 | Method of storing photographic processing solution | KONISHIROKU PHOTO IND (JP) | 1994-03-30 | — | — | EP | disclosed |
| EP-0196091-B1 | METHOD OF PROCESSING LIGHT-SENSITIVE SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL | KONICA CORPORATION (JP) | 1992-10-28 | — | — | EP | disclosed |