Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.46 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.46 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.44 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.39 |
| ▸ | P2RY12 known ✓ | Q9H244 | 1/20 | 0.36 |
| ▸ | DUSP5 | Q16690 | 3/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11199053 | 1.00 | DUSP5 (0.50) | DUSP5NR4A1CDK2ADAMTS4ALDH1A1 | |
| SCHEMBL9805973 | 0.96 | PTGS1 (0.48) | DUSP5NR4A1CDK2ADAMTS4ALDH1A1 | |
| SCHEMBL9509844 | 0.96 | NR4A1 (0.50) | DUSP5NR4A1CDK2ADAMTS4ALDH1A1 | |
| Lithium Ion SCHEMBL29083050 | 0.96 | DUSP5 (0.46) | DUSP5NR4A1CDK2ADAMTS4ALDH1A1 | |
| Potassium Ion SCHEMBL5191230 | 0.96 | NR4A1 (0.50) | DUSP5NR4A1CDK2ADAMTS4ALDH1A1 | |
| Water SCHEMBL28391333 | 0.94 | PTGS1 (0.47) | DUSP5NR4A1CDK2ADAMTS4ALDH1A1 | |
| SCHEMBL8144698 | 0.91 | DUSP5 (0.44) | DUSP5NR4A1CDK2ADAMTS4ALDH1A1 | |
| SCHEMBL7784950 | 0.89 | DUSP5 (0.50) | DUSP5NR4A1CDK2TDP1PKLR | |
| SCHEMBL29241949 | 0.83 | PKLR (0.51) | DUSP5NR4A1CDK2ADAMTS4ALDH1A1 | |
| Phenolsulphonic Acid SCHEMBL3700204 | 0.82 | PTGS1 (0.52) | DUSP5NR4A1CDK2ALDH1A1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116036383-A | Ultra-smooth hydrophilic coating for interventional guide wire and preparation method thereof | 佛山市其右医疗科技有限公司 | 2023-05-02 | — | — | CN | claimed |
| WO-2004108414-A2 | LITHOGRAPHIC PRINTING PLATE SYSTEM AND METHOD FOR MANUFACTURING THE PLATE SYSTEM | DIGITAL MIND S.R.L. (IT) | 2004-12-16 | — | — | WO | claimed |
| EP-0757715-B1 | CELLULASE FABRIC-CONDITIONING COMPOSITIONS | PROCTER & GAMBLE (US) | 1999-12-08 | — | — | EP | claimed |
| EP-0757715-A1 | CELLULASE FABRIC-CONDITIONING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1997-02-12 | — | — | EP | claimed |
| WO-1995029980-A1 | CELLULASE FABRIC-CONDITIONING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1995-11-09 | — | — | WO | claimed |
| US-5445747-A | Containing fabric softener, perfume selected to cover odors | THE PROCTER & GAMBLE COMPANY (US) | 1995-08-29 | — | — | US | claimed |
| JP-53142873-A | — | — | None | — | — | JP | disclosed |
| CN-116640465-A | High-light-resistance titanium dioxide and preparation method thereof | 河南佰利联新材料有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-116036383-A | Ultra-smooth hydrophilic coating for interventional guide wire and preparation method thereof | 佛山市其右医疗科技有限公司 | 2023-05-02 | — | — | CN | disclosed |
| US-20120065114-A1 | AMINE REACTION COMPOUNDS COMPRISING ONE OR MORE ACTIVE INGREDIENT | THE PROCTER & GAMBLE COMPANY (US) | 2012-03-15 | — | — | US | disclosed |
| US-20110268818-A1 | NGAL-BINDING SIDEROPHORES AND USE THEREOF TO TREAT IRON DEFICIENCY AND IRON OVERLOAD | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2011-11-03 | — | — | US | disclosed |
| US-20110207643-A1 | AMINE REACTION COMPOUNDS COMPRISING ONE OR MORE ACTIVE INGREDIENT | THE PROCTER & GAMBLE COMPANY (US) | 2011-08-25 | — | — | US | disclosed |
| EP-2330897-A1 | NGAL-BINDING SIDEROPHORES AND USE THEREOF TO TREAT IRON DEFICIENCY AND IRON OVERLOAD | The Trustees of Columbia University in the City of New York (US) | 2011-06-15 | — | — | EP | disclosed |
| WO-1996015212-A1 | CONCENTRATED BIODEGRADABLE QUATERNARY AMMONIUM FABRIC SOFTENER COMPOSITIONS CONTAINING INTERMEDIATE IODINE VALUE FATTY ACID CHAINS | THE PROCTER & GAMBLE COMPANY (US) | 1996-05-23 | — | — | WO | disclosed |
| WO-1996012785-A1 | FABRIC SOFTENER COMPOSITIONS WITH REDUCED ENVIRONMENTAL IMPACT | THE PROCTER & GAMBLE COMPANY (US) | 1996-05-02 | — | — | WO | disclosed |
| US-5474690-A | Storage stability, viscosity stability | THE PROCTER & GAMBLE COMPANY (US) | 1995-12-12 | — | — | US | disclosed |
| WO-1995029980-A1 | CELLULASE FABRIC-CONDITIONING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1995-11-09 | — | — | WO | disclosed |
| WO-1995024460-A1 | FABRIC SOFTENER COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1995-09-14 | — | — | WO | disclosed |
| US-5445747-A | Containing fabric softener, perfume selected to cover odors | THE PROCTER & GAMBLE COMPANY (US) | 1995-08-29 | — | — | US | disclosed |
| JP-S53142873-A | ETCHING METHOD OF GAAS GROUP COMPOUND SEMICONDUCTOR CRYSTAL | TOSHIBA CORP | 1978-12-12 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207643-A1 | AMINE REACTION COMPOUNDS COMPRISING ONE OR MORE ACTIVE INGREDIENT | MAOA, MAOB, CMA1 | CA1 1127/4885CA2 1348/4885PTGS1 119/4885 |
| US-20110268818-A1 | NGAL-BINDING SIDEROPHORES AND USE THEREOF TO TREAT IRON DEFICIENCY AND IRON OVERLOAD | SLC40A1, HAMP, TFRC | CA1 2702/4885CA2 1383/4885PTGS1 1616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.