Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL201995 | 0.84 | THRB (0.32) | — | |
| SCHEMBL809315 | 0.83 | TGFBR1 (0.32) | — | |
| Bromide SCHEMBL4456365 | 0.81 | DNM1 (0.32) | — | |
| Water SCHEMBL7715787 | 0.81 | TGFBR1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL717635 | 0.71 | THRB (0.33) | — | |
| Acrylamide SCHEMBL28870529 | 0.70 | ZDHHC20 (0.41) | — | |
| SCHEMBL9451788 | 0.69 | TGFBR1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL10949727 | 0.69 | TGFBR1 (0.33) | — | |
| Iodide SCHEMBL27449413 | 0.68 | TGFBR1 (0.32) | — | |
| Methacrylic Acid SCHEMBL28895001 | 0.68 | TDP1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619271-B1 | NON-FLUOROPOLYMER SURFACE PROTECTION COMPOSITION | PROCTER & GAMBLE (US) | 2018-05-16 | — | — | EP | disclosed |
| EP-3286146-A1 | PAINT DETACKIFIER COMPOSITION AND USES THEREOF | Ecolab USA Inc. (US) | 2018-02-28 | — | — | EP | disclosed |
| EP-2619299-B1 | FABRIC CARE FORMULATIONS AND METHODS | WACKER CHEMIE AG (DE) | 2018-02-28 | — | — | EP | disclosed |
| EP-2619272-B1 | NON-FLUOROPOLYMER SURFACE PROTECTION COMPOSITION | PROCTER & GAMBLE (US) | 2017-12-06 | — | — | EP | disclosed |
| WO-2016172510-A1 | PAINT DETACKIFIER COMPOSITION AND USES THEREOF | ECOLAB USA INC. (US) | 2016-10-27 | — | — | WO | disclosed |
| US-8637442-B2 | Non-fluoropolymer surface protection composition comprising a polyorganosiloxane-silicone resin mixture | THE PROCTER & GAMBLE COMPANY (US) | 2014-01-28 | — | — | US | disclosed |
| US-8633146-B2 | Non-fluoropolymer surface protection composition comprising a polyorganosiloxane-silicone resin mixture | THE PROCTER & GAMBLE COMPANY (US) | 2014-01-21 | — | — | US | disclosed |
| US-20130292600-A1 | NON-FLUOROPOLYMER SURFACE PROTECTION COMPOSITION | PROCTER & GAMBLE (US) | 2013-11-07 | — | — | US | disclosed |
| US-20130296218-A1 | NON-FLUOROPOLYMER SURFACE PROTECTION COMPOSITION | PROCTER & GAMBLE (US) | 2013-11-07 | — | — | US | disclosed |
| EP-2619299-A2 | FABRIC CARE FORMULATIONS AND METHODS | The Procter and Gamble Company (US) | 2013-07-31 | — | — | EP | disclosed |
| EP-2619272-A1 | NON-FLUOROPOLYMER SURFACE PROTECTION COMPOSITION | The Procter and Gamble Company (US) | 2013-07-31 | — | — | EP | disclosed |
| EP-2619271-A1 | NON-FLUOROPOLYMER SURFACE PROTECTION COMPOSITION | The Procter and Gamble Company (US) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012040171-A1 | NON-FLUOROPOLYMER SURFACE PROTECTION COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 2012-03-29 | — | — | WO | disclosed |
| WO-2012040130-A1 | NON-FLUOROPOLYMER SURFACE PROTECTION COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 2012-03-29 | — | — | WO | disclosed |
| US-20120077725-A1 | FABRIC CARE FORMULATIONS AND METHODS | THE PROCTER & GAMBLE COMPANY | 2012-03-29 | — | — | US | disclosed |
| WO-2012040131-A2 | FABRIC CARE FORMULATIONS AND METHODS | THE PROCTER & GAMBLE COMPANY (US) | 2012-03-29 | — | — | WO | disclosed |
| US-20120067766-A1 | NON-FLUOROPOLYMER SURFACE PROTECTION COMPOSITION | PROCTER & GAMBLE COMPANY, THE | 2012-03-22 | — | — | US | disclosed |
| US-20120071382-A1 | NON-FLUOROPOLYMER SURFACE PROTECTION COMPOSITION | PROCTER & GAMBLE COMPANY, THE | 2012-03-22 | — | — | US | disclosed |