Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 3/20 | 0.48 |
| ▸ | PREP | P48147 | 4/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 4/20 | 0.44 |
| ▸ | CTSL | P07711 | 3/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL795453 | 0.87 | FPR2 (0.52) | CASP3CASP1CTSKCTSLCTSS | |
| SCHEMBL795454 | 0.87 | FPR2 (0.52) | CASP3CASP1CTSKCTSLCTSS | |
| SCHEMBL15023721 | 0.82 | CASP3 (0.43) | CASP3CASP1PREPCTSKCTSL | |
| SCHEMBL19255760 | 0.81 | CASP1 (0.48) | CASP3CASP1PREPDPP4KCNH2 | |
| SCHEMBL13043811 | 0.80 | CASP3 (0.53) | CASP3CASP1ALDH1A1GAACTSK | |
| SCHEMBL14337553 | 0.80 | CASP3 (0.53) | CASP3CASP1ALDH1A1GAACTSK | |
| SCHEMBL6199732 | 0.79 | CASP3 (0.60) | CASP3CASP1ALDH1A1GAACTSK | |
| SCHEMBL2551898 | 0.78 | DPP4 (0.62) | DPP4KCNH2DPP7ALDH1A1GAA | |
| SCHEMBL5650545 | 0.78 | CASP3 (0.64) | CASP3CASP1ALDH1A1GAACTSK | |
| SCHEMBL14641301 | 0.78 | CASP3 (0.64) | CASP3CASP1ALDH1A1GAACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130184257-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | ARRAY BIOPHARMA, INC. | 2013-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130184257-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | GPR119, GPR139, GPR180 | CASP3 3751/4885CASP1 2334/4885PREP 713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.