Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acid Blue 25. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY4 known ✓ | P51582 | 13/20 | 1.00 |
| ▸ | P2RY12 known ✓ | Q9H244 | 9/20 | 1.00 |
| ▸ | P2RY2 known ✓ | P41231 | 7/20 | 1.00 |
| ▸ | P2RY6 known ✓ | Q15077 | 4/20 | 1.00 |
| ▸ | P2RY1 known ✓ | P47900 | 2/20 | 1.00 |
| ▸ | CDK2 | P24941 | 2/20 | 1.00 |
| ▸ | MET | P08581 | 3/20 | 0.86 |
| ▸ | HGF | P14210 | 2/20 | 0.86 |
| ▸ | ENTPD1 | P49961 | 2/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acid Blue 25 SCHEMBL29355038 | 1.00 | P2RY4 (1.00) | P2RY4P2RY12P2RY2P2RY6CDK2 | |
| SCHEMBL29395314 | 0.93 | P2RY12 (1.00) | P2RY4P2RY12P2RY2P2RY6CDK2 | |
| SCHEMBL3019529 | 0.93 | P2RY12 (1.00) | P2RY4P2RY12P2RY2P2RY6CDK2 | |
| SCHEMBL30504038 | 0.93 | P2RY12 (1.00) | P2RY4P2RY12P2RY2P2RY6CDK2 | |
| SCHEMBL3029895 | 0.92 | MET (0.93) | P2RY4P2RY12P2RY2P2RY6CDK2 | |
| SCHEMBL3026030 | 0.92 | P2RY12 (1.00) | P2RY4P2RY12P2RY2P2RY6CDK2 | |
| SCHEMBL791055 | 0.91 | P2RY4 (0.82) | P2RY4P2RY12P2RY2P2RY6CDK2 | |
| SCHEMBL3030129 | 0.90 | P2RY4 (1.00) | P2RY4P2RY12P2RY2P2RY6CDK2 | |
| SCHEMBL3020870 | 0.90 | P2RY4 (0.82) | P2RY4P2RY12P2RY2P2RY6CDK2 | |
| SCHEMBL3021097 | 0.90 | P2RY4 (1.00) | P2RY4P2RY12P2RY2P2RY6CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616449-A1 | ANTHRAQUINONE COMPOUNDS AND THEIR USES | Dundalk Institute of Technology (IE) | 2013-07-24 | — | — | EP | claimed |
| WO-2012035122-A1 | ANTHRAQUINONE COMPOUNDS AND THEIR USES | DUNDALK INSTITUTE OF TECHNOLOGY (IE) | 2012-03-22 | — | — | WO | claimed |
| JP-4750804-B2 | — | — | 2011-08-17 | — | — | JP | claimed |
| US-20080306026-A1 | Capsule Formulation | SYNGENTA CROP PROTECTION LLC | 2008-12-11 | — | — | US | claimed |
| JP-2008531514-A | — | — | 2008-08-14 | — | — | JP | claimed |
| EP-1850664-A2 | PESTICIDAL CAPSULE FORMULATION | Syngeta Participations AG (CH) | 2007-11-07 | — | — | EP | claimed |
| WO-2006089747-A2 | PRESTICIDAL CAPSULE FORMULATION | SYNGENTA PARTICIPATIONS AG (CH) | 2006-08-31 | — | — | WO | claimed |
| EP-0525073-B1 | ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA | DU PONT (US) | 1994-05-25 | — | — | EP | claimed |
| EP-4426280-B1 | PROTECTION AGAINST ARTHROPOD PARASITES WITH PURINERGIC RECEPTOR (OPR) ANTAGONISTS | GURBA ALEXANDRE (CH) | 2026-03-18 | — | — | EP | disclosed |
| US-12319037-B2 | Transparent polymer film with discoloration compensation | KLÖCKNER PENTAPLAST GMBH (DE) | 2025-06-03 | — | — | US | disclosed |
| US-20250057791-A1 | PROTECTION AGAINST ARTHROPOD PARASITES WITH PURINERGIC RECEPTOR (OPR) ANTAGONISTS | GURBA ALEXANDRE (CH) | 2025-02-20 | — | — | US | disclosed |
| US-20240083151-A1 | TRANSPARENT POLYMER FILM WITH DISCOLORATION COMPENSATION | KLÖCKNER PENTAPLAST GMBH (DE) | 2024-03-14 | — | — | US | disclosed |
| US-11858241-B2 | Transparent polymer film with discolouration compensation | KLÖCKNER PENTAPLAST GMBH (DE) | 2024-01-02 | — | — | US | disclosed |
| WO-2023111938-A1 | PROTECTION AGAINST ARTHROPOD PARASITES WITH PURINERGIC RECEPTOR (OPR) ANTAGONISTS | GURBA, Alexandre (CH) | 2023-06-22 | — | — | WO | disclosed |
| EP-1002021-A1 | DISPERSING AGENTS AND DISPERSIONS MADE THEREFROM | ICI AMERICAS INC. (US) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999005225-A1 | DISPERSING AGENTS AND DISPERSIONS MADE THEREFROM | ICI AMERICAS INC. (US) | 1999-02-04 | — | — | WO | disclosed |
| EP-0525073-B1 | ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA | DU PONT (US) | 1994-05-25 | — | — | EP | disclosed |
| EP-0525073-A1 | ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA. | DU PONT (US) | 1993-02-03 | — | — | EP | disclosed |
| WO-1991015954-A1 | ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-10-31 | — | — | WO | disclosed |
| US-4289496-A | LOW LIQUID TO MATERIAL RATIO RESULTING IN UNIFORMITY OF FINISHING | SANDOZ LTD. (CH) | 1981-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250057791-A1 | PROTECTION AGAINST ARTHROPOD PARASITES WITH PURINERGIC RECEPTOR (OPR) ANTAGONISTS | P2RX2, P2RX3, P2RX1 | P2RY4 12/4885P2RY12 16/4885P2RY2 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.