Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 7/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.53 |
| ▸ | GSK3A | P49840 | 2/20 | 0.51 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.51 |
| ▸ | PNP | P00491 | 1/20 | 0.47 |
| ▸ | KRAS | P01116 | 6/20 | 0.47 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15841335 | 0.99 | HINT1 (0.52) | HINT1TAS1R3TAS1R1GSK3ARPS6KA3 | |
| SCHEMBL7915394 | 0.84 | HINT1 (0.71) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL20215732 | 0.80 | TAS1R3 (0.43) | HINT1TAS1R3TAS1R1 | |
| SCHEMBL15850633 | 0.80 | TAS1R3 (0.43) | HINT1TAS1R3TAS1R1 | |
| SCHEMBL14727516 | 0.80 | TAS1R3 (0.43) | HINT1TAS1R3TAS1R1 | |
| SCHEMBL19981038 | 0.80 | TAS1R3 (0.43) | HINT1TAS1R3TAS1R1 | |
| SCHEMBL13009985 | 0.80 | HINT1 (0.56) | HINT1TAS1R3TAS1R1GSK3ARPS6KA3 | |
| SCHEMBL17853311 | 0.80 | TAS1R3 (0.44) | HINT1TAS1R3TAS1R1NT5ETAAR1 | |
| SCHEMBL15892169 | 0.80 | TAS1R3 (0.44) | HINT1TAS1R3TAS1R1NT5ETAAR1 | |
| SCHEMBL2106148 | 0.79 | TYMP (0.42) | HINT1TAS1R3TAS1R1GSK3ARPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1995253-B1 | METHOD FOR DETACHING PROTECTING GROUP ON NUCLEIC ACID | NIPPON SHINYAKU CO LTD (JP) | 2016-12-21 | — | — | EP | disclosed |
| EP-2053054-B1 | METHOD FOR INTRODUCING NUCLEIC-ACID-PROTECTING GROUP | NIPPON SHINYAKU CO LTD (JP) | 2014-12-17 | — | — | EP | disclosed |
| EP-1795536-B1 | PHOSPHORAMIDITE COMPOUND AND METHOD FOR PRODUCING OLIGO-RNA | NIPPON SHINYAKU CO LTD (JP) | 2012-05-02 | — | — | EP | disclosed |
| US-8158774-B2 | Method for introducing a nucleic-acid protecting group | NIPPON SHINYAKU CO., LTD. (JP) | 2012-04-17 | — | — | US | disclosed |
| US-8158775-B2 | Method for detaching protecting group on nucleic acid | NIPPON SHINYAKU CO., LTD. (JP) | 2012-04-17 | — | — | US | disclosed |
| US-20090312534-A1 | METHOD FOR REMOVAL OF NUCLEIC ACID-PROTECTING GROUP | NIPPON SHINYAKU CO., LTD. (JP) | 2009-12-17 | — | — | US | disclosed |
| US-20090286970-A1 | METHOD FOR INTRODUCING A NUCLEIC-ACID PROTECTING GROUP | NIPPON SHINYAKU CO., LTD. (JP) | 2009-11-19 | — | — | US | disclosed |
| US-20090149645-A1 | METHOD FOR DETACHING PROTECTING GROUP ON NUCLEIC ACID | NIPPON SHINYAKU CO., LTD. (JP) | 2009-06-11 | — | — | US | disclosed |
| US-20090137790-A1 | METHOD OF CAPPING OLIGONUCLEIC ACID | NIPPON SHINYAKU CO., LTD. (JP) | 2009-05-28 | — | — | US | disclosed |
| EP-2053054-A1 | METHOD FOR INTRODUCING NUCLEIC-ACID-PROTECTING GROUP | Nippon Shinyaku Co., Ltd. (JP) | 2009-04-29 | — | — | EP | disclosed |
| EP-2017282-A1 | METHOD OF CAPPING OLIGONUCLEIC ACID | Nippon Shinyaku Co., Ltd. (JP) | 2009-01-21 | — | — | EP | disclosed |
| EP-1995252-A1 | METHOD FOR REMOVAL OF NUCLEIC ACID-PROTECTING GROUP | Nippon Shinyaku Co., Ltd. (JP) | 2008-11-26 | — | — | EP | disclosed |
| EP-1995253-A1 | METHOD FOR DETACHING PROTECTING GROUP ON NUCLEIC ACID | Nippon Shinyaku Co., Ltd. (JP) | 2008-11-26 | — | — | EP | disclosed |
| US-20070282097-A1 | Phosphoramidite Compound And Method For Producing Oligo-Rna | NIPPON SHINYAKU CO., LTD. (JP) | 2007-12-06 | — | — | US | disclosed |
| EP-1795536-A1 | PHOSPHORAMIDITE COMPOUND AND METHOD FOR PRODUCING OLIGO-RNA | Nippon Shinyaku Co., Ltd. (JP) | 2007-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312534-A1 | METHOD FOR REMOVAL OF NUCLEIC ACID-PROTECTING GROUP | NSUN2, RNASEH1, RNASE1 | HINT1 499/4885TAS1R3 3036/4885TAS1R1 2551/4885 |
| US-20090137790-A1 | METHOD OF CAPPING OLIGONUCLEIC ACID | RNGTT, DUT, ADAR | HINT1 554/4885TAS1R3 4816/4885TAS1R1 4860/4885 |
| US-20070282097-A1 | Phosphoramidite Compound And Method For Producing Oligo-Rna | NSUN2, NSUN3, XRN2 | HINT1 309/4885TAS1R3 2238/4885TAS1R1 2039/4885 |
| US-20090286970-A1 | METHOD FOR INTRODUCING A NUCLEIC-ACID PROTECTING GROUP | RNASEH1, SNRPB2, SNRPA1 | HINT1 403/4885TAS1R3 2278/4885TAS1R1 1715/4885 |
| US-20090149645-A1 | METHOD FOR DETACHING PROTECTING GROUP ON NUCLEIC ACID | DNASE1, DNASE1L3, NSUN2 | HINT1 1590/4885TAS1R3 3167/4885TAS1R1 4174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.