Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PORCN | Q9H237 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956113 | 0.88 | MMP1 (0.42) | TBXAS1KDM4EPOLBHPGDCYP3A4 | |
| SCHEMBL7956127 | 0.87 | MMP9 (0.46) | KDM4EPOLBHPGDCYP3A4CYP2D6 | |
| SCHEMBL7945733 | 0.83 | PGR (0.43) | TBXAS1KDM4EPOLBHPGDCYP3A4 | |
| SCHEMBL7955821 | 0.81 | MMP2 (0.46) | ACP1KDM4EUSP2POLBHPGD | |
| SCHEMBL7956056 | 0.79 | ALDH1A1 (0.51) | KDM4EALDH1A1MAPTMMP9MMP8 | |
| SCHEMBL7959404 | 0.77 | MMP2 (0.56) | PORCNMMP9MMP13MMP1 | |
| SCHEMBL1381142 | 0.75 | MMP2 (0.41) | ACP1KDM4EUSP2POLBHPGD | |
| SCHEMBL7952565 | 0.75 | LMNA (0.55) | ALDH1A1MAPTMMP9MMP13 | |
| SCHEMBL7955839 | 0.74 | MMP2 (0.42) | KDM4ETSHRALDH1A1MAPTMMP9 | |
| Hydroxyamine SCHEMBL1380759 | 0.74 | MMP2 (0.40) | ACP1KDM4EUSP2POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277987-B1 | FOR INHIBITING MATRIX-DEGRADING METALLOPROTEINASES IN MAMMALS | NOVARTIS AG (CH) | 2001-08-21 | — | — | US | disclosed |