Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7964943 | 0.85 | LTA4H (0.33) | CCR1HTR1A | |
| SCHEMBL7964944 | 0.84 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL7965117 | 0.78 | CYP1A2 (0.58) | ABCB1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7963395 | 0.77 | LMNA (0.44) | ABCB1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7962210 | 0.76 | TP53 (0.56) | MEN1KMT2ASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL7962698 | 0.74 | L3MBTL1 (0.46) | MEN1KMT2ASMN1; SMN2MAPK1HSD17B10 | |
| Fumaric Acid SCHEMBL7966212 | 0.74 | ABCB1 (0.51) | ABCB1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7962746 | 0.72 | SMN1; SMN2 (0.47) | SMN1; SMN2NPSR1MAPTMAPK1HSD17B10 | |
| SCHEMBL8019951 | 0.70 | MEN1 (0.49) | ABCB1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8141686 | 0.70 | ABCB1 (0.40) | ABCB1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| WO-2000006166-A1 | 5-HT1F ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |