Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | FGB | P02675 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966334 | 0.75 | KDM4E (0.36) | MAPTLMNAHSP90AA1HTTSMN1; SMN2 | |
| SCHEMBL1388444 | 0.68 | FGB (0.38) | MAPTLMNAHSP90AA1HTTSMN1; SMN2 | |
| SCHEMBL7963227 | 0.68 | LMNA (0.36) | MAPTLMNAHSP90AA1HTTSMN1; SMN2 | |
| SCHEMBL9434365 | 0.68 | FGB (0.42) | MAPTLMNAHSP90AA1HTTSMN1; SMN2 | |
| SCHEMBL8911552 | 0.68 | SMN1; SMN2 (0.36) | MAPTLMNAHSP90AA1HTTSMN1; SMN2 | |
| SCHEMBL9434368 | 0.68 | SMN1; SMN2 (0.36) | MAPTLMNAHSP90AA1HTTSMN1; SMN2 | |
| SCHEMBL9434910 | 0.67 | HRH3 (0.37) | MAPTLMNAHSP90AA1HTTSMN1; SMN2 | |
| SCHEMBL9434110 | 0.65 | SMN1; SMN2 (0.36) | MAPTLMNAHSP90AA1HTTSMN1; SMN2 | |
| SCHEMBL8536893 | 0.65 | MAPT (0.52) | MAPTLMNAHSP90AA1HTTSMN1; SMN2 | |
| SCHEMBL9435019 | 0.65 | ALDH1A1 (0.35) | MAPTLMNAHSP90AA1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201129-B1 | ANTICARCINOGENIC AGENTS | UNIV. COLLEGE CARDIFF CONSULTANTS (GB) | 2001-03-13 | — | — | US | disclosed |