Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | DHFR | P00374 | 5/20 | 0.36 |
| ▸ | TYMS | P04818 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968977 | 0.82 | MAOB (0.36) | CA12CA9DHFRALDH1A1MEN1 | |
| SCHEMBL7968952 | 0.82 | KDM4E (0.38) | GPR84CA12CA9DHFRALDH1A1 | |
| SCHEMBL7972384 | 0.79 | KDM4E (0.35) | GPR84DHFRALDH1A1MEN1MAPT | |
| SCHEMBL7966642 | 0.77 | CYP1A2 (0.41) | DHFRTYMSALDH1A1MEN1MAPT | |
| SCHEMBL7965270 | 0.75 | DHFR (0.47) | GPR84DHFRTYMSMMP2MMP3 | |
| SCHEMBL7972422 | 0.73 | GPR84 (0.39) | GPR84ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL6026174 | 0.72 | ESR2 (0.40) | TYMSALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL6026268 | 0.72 | CFTR (0.39) | TYMSALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL7955950 | 0.70 | DHFR (0.49) | DHFRTYMSALDH1A1KDM4EHPGD | |
| SCHEMBL7956293 | 0.70 | TLR8 (0.39) | GPR84CA12CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |