Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956141 | 0.83 | HSD11B1 (0.37) | — | |
| SCHEMBL7968407 | 0.73 | POLB (0.46) | ARMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL7965276 | 0.71 | HSPB1 (0.40) | ARMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL6026229 | 0.71 | ADK (0.39) | ARMAPTALDH1A1POLBMAPK1 | |
| SCHEMBL6932241 | 0.70 | PTGER3 (0.36) | PGRARALDH1A1 | |
| SCHEMBL7968980 | 0.69 | PTGER3 (0.35) | MEN1KMT2AGAA | |
| SCHEMBL7968467 | 0.68 | MAPT (0.39) | ARMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL7539856 | 0.68 | ABCG2 (0.37) | MAPTPOLBMAPK1 | |
| SCHEMBL6934430 | 0.68 | AKR1C2 (0.36) | MEN1KMT2A | |
| SCHEMBL7966269 | 0.65 | LMNA (0.40) | MAPTALDH1A1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |