Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | GUSB | P08236 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971836 | 0.85 | APP (0.49) | MAPTKMT2AALDH1A1POLBCTDSP1 | |
| SCHEMBL7971494 | 0.82 | ALDH1A1 (0.33) | MAPTKMT2AF7F3ALDH1A1 | |
| SCHEMBL7965276 | 0.73 | HSPB1 (0.40) | MAPTKMT2AALDH1A1POLBCTDSP1 | |
| SCHEMBL7967042 | 0.71 | PGR (0.36) | MAPTKMT2AESR1ESR2ALDH1A1 | |
| SCHEMBL7968407 | 0.71 | POLB (0.46) | MAPTKMT2AALDH1A1POLBAPP | |
| SCHEMBL7972438 | 0.69 | ESR2 (0.42) | MAPTKMT2AESR1ESR2POLB | |
| SCHEMBL7972386 | 0.69 | MAPT (0.40) | MAPTKMT2AALDH1A1POLBMEN1 | |
| SCHEMBL7968467 | 0.69 | MAPT (0.39) | MAPTKMT2AALDH1A1POLBCA12 | |
| SCHEMBL7539856 | 0.69 | ABCG2 (0.37) | MAPTPOLBCA9 | |
| SCHEMBL7966269 | 0.67 | LMNA (0.40) | MAPTALDH1A1POLBCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |