Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988231 | 0.96 | NPC1 (0.47) | ADORA3NPC1RAB9AADORA1KMT2A | |
| SCHEMBL7974265 | 0.91 | MCHR1 (0.47) | ADORA3NPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL7975241 | 0.89 | GAA (0.50) | ADORA3NPC1RAB9AADORA2AADORA1 | |
| SCHEMBL7985340 | 0.89 | NTRK1 (0.51) | ADORA3NPC1RAB9AMAPTKMT2A | |
| SCHEMBL7984937 | 0.89 | ADORA3 (0.52) | ADORA3NPC1RAB9AMAPTKMT2A | |
| SCHEMBL7973996 | 0.88 | POLB (0.49) | ADORA3NPC1RAB9AMAPTKMT2A | |
| SCHEMBL7988029 | 0.87 | IDO1 (0.47) | ADORA3NPC1RAB9AHDAC1HDAC6 | |
| SCHEMBL7985255 | 0.86 | ALDH1A1 (0.51) | NPC1RAB9AMAPTL3MBTL1KMT2A | |
| SCHEMBL7985682 | 0.84 | GAA (0.46) | RAB9AMAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL7985249 | 0.83 | MAPT (0.48) | NPC1RAB9AMAPTL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |