Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 2/20 | 0.40 |
| ▸ | DHPS | P49366 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974286 | 0.90 | DHPS (0.49) | CLK4L3MBTL1KMT2AMEN1GBA1 | |
| SCHEMBL7989420 | 0.89 | MET (0.45) | DHPSSMN1; SMN2LMNAHSD17B10TP53 | |
| SCHEMBL7988934 | 0.89 | CYP1A2 (0.47) | KMT2AMEN1KDRDHPSSMN1; SMN2 | |
| SCHEMBL7974237 | 0.89 | KIF11 (0.42) | KMT2AMEN1DHPSHTTSMN1; SMN2 | |
| SCHEMBL7984717 | 0.88 | SMN1; SMN2 (0.46) | KMT2AMEN1HTTSMN1; SMN2LMNA | |
| SCHEMBL7985826 | 0.86 | NPC1 (0.41) | KMT2AMEN1HTTSMN1; SMN2LMNA | |
| SCHEMBL7988659 | 0.84 | P2RX7 (0.41) | L3MBTL1KDRDHPSHTTSMN1; SMN2 | |
| SCHEMBL7985565 | 0.83 | HDAC6 (0.40) | KMT2AMEN1HTTSMN1; SMN2LMNA | |
| SCHEMBL7984423 | 0.83 | SMN1; SMN2 (0.38) | KMT2AMEN1HTTSMN1; SMN2LMNA | |
| SCHEMBL7991597 | 0.83 | PDE4B (0.39) | L3MBTL1HTTSMN1; SMN2LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |