Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | DHPS | P49366 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974286 | 0.90 | DHPS (0.49) | CYP11B1CYP11B2POLBABCG2MAPT | |
| SCHEMBL7984769 | 0.89 | CLK4 (0.44) | CYP11B1CYP11B2ABCG2MAPTTP53 | |
| SCHEMBL7985334 | 0.89 | ABCG2 (0.46) | CYP11B1CYP11B2ABCG2KDM4EDHPS | |
| SCHEMBL7986521 | 0.88 | CYP11B1 (0.47) | METCYP11B1CYP11B2MAPTTP53 | |
| SCHEMBL7985275 | 0.86 | MET (0.46) | METCYP11B1CYP11B2HDAC6 | |
| SCHEMBL7974237 | 0.86 | KIF11 (0.42) | ABCG2MAPTTP53KDM4EDHPS | |
| SCHEMBL7984281 | 0.86 | MET (0.52) | METCYP11B1CYP11B2KDM4ESMN1; SMN2 | |
| SCHEMBL7988734 | 0.84 | MET (0.44) | METCYP11B1CYP11B2ABCG2KDM4E | |
| SCHEMBL7988659 | 0.84 | P2RX7 (0.41) | CYP11B1CYP11B2ABCG2MAPTCYP3A4 | |
| SCHEMBL7985118 | 0.84 | ADRB2 (0.41) | POLBABCG2MAPTTP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |