Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | DHPS | P49366 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | LHCGR | P22888 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984769 | 0.89 | CLK4 (0.44) | HDAC1HDAC6DHPSMAPTLMNA | |
| SCHEMBL7974490 | 0.88 | NR1H4 (0.47) | NR1H4ABCC8KCNJ11ALDH1A1TP53 | |
| SCHEMBL7984932 | 0.87 | ABCC8 (0.43) | KIF11NR1H4ABCC8KCNJ11HDAC6 | |
| SCHEMBL7974286 | 0.87 | DHPS (0.49) | DHPSMAPTLMNAALDH1A1TP53 | |
| SCHEMBL7989420 | 0.86 | MET (0.45) | HDAC1HDAC6DHPSMAPTLMNA | |
| SCHEMBL7974277 | 0.84 | NR1H4 (0.44) | NR1H4ABCC8KCNJ11HDAC1HDAC6 | |
| SCHEMBL7991400 | 0.84 | NR1H4 (0.43) | NR1H4ABCC8KCNJ11MAPTLMNA | |
| SCHEMBL7985010 | 0.84 | NR1H4 (0.43) | NR1H4ABCC8KCNJ11HDAC1HDAC6 | |
| SCHEMBL7988522 | 0.83 | NR1H4 (0.44) | NR1H4ABCC8KCNJ11MAPTLMNA | |
| SCHEMBL7992267 | 0.83 | ICMT (0.44) | NR1H4ABCC8KCNJ11HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |