Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 3/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987441 | 0.84 | MEN1 (0.49) | CYP11B2GAARAB9AMMP13 | |
| SCHEMBL7988530 | 0.82 | SMN1; SMN2 (0.46) | CYP11B2LMNAGAARAB9A | |
| SCHEMBL7986400 | 0.81 | YTHDC1 (0.47) | YTHDC1CYP11B2LOXL2LMNAGAA | |
| SCHEMBL7987743 | 0.81 | SCD (0.50) | CYP11B2LMNAGAA | |
| SCHEMBL2183153 | 0.81 | L3MBTL1 (0.48) | CYP11B2GAAMMP13 | |
| SCHEMBL7987690 | 0.80 | PKM (0.43) | CYP11B2LMNAGAARAB9A | |
| SCHEMBL7987245 | 0.80 | ROCK2 (0.47) | LMNA | |
| SCHEMBL5483136 | 0.79 | PKM (0.59) | CYP11B2LMNAGAA | |
| SCHEMBL7975121 | 0.79 | ABCC8 (0.47) | CYP11B2GAA | |
| Hydrochloric Acid SCHEMBL7987445 | 0.78 | PKM (0.57) | CYP11B2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |