Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | QPCT | Q16769 | 2/20 | 0.47 |
| ▸ | QPCTL | Q9NXS2 | 2/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987927 | 0.87 | HSP90AA1 (0.53) | FYNALDH1A1DHFRSMN1; SMN2 | |
| SCHEMBL7987441 | 0.84 | MEN1 (0.49) | ROCK2QPCTQPCTLALDH1A1L3MBTL1 | |
| SCHEMBL7984239 | 0.82 | ADRA1D (0.52) | ROCK2QPCTQPCTLLMNA | |
| SCHEMBL7985508 | 0.80 | ALDH1A1 (0.43) | ROCK2QPCTQPCTLMAPK10ALDH1A1 | |
| SCHEMBL7988530 | 0.80 | SMN1; SMN2 (0.46) | ALDH1A1HTTLMNASMN1; SMN2HDAC3 | |
| SCHEMBL7985129 | 0.80 | YTHDC1 (0.50) | LMNA | |
| SCHEMBL7987743 | 0.78 | SCD (0.50) | HTTLMNASMN1; SMN2HDAC4HDAC1 | |
| SCHEMBL7975372 | 0.78 | ALDH1A1 (0.51) | ALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL7987490 | 0.78 | ADORA2A (0.44) | ALDH1A1SMN1; SMN2CYP19A1 | |
| SCHEMBL7989347 | 0.77 | CYP11B1 (0.44) | ALDH1A1LMNAHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |