Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | MC5R | P33032 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | ICMT | O60725 | 4/20 | 0.40 |
| ▸ | VDR | P11473 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5483136 | 0.83 | PKM (0.59) | ADORA2AGAAPKMTSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL7987445 | 0.82 | PKM (0.57) | ADORA2AGAAPKMTSHRALDH1A1 | |
| SCHEMBL7984484 | 0.81 | PKM (0.50) | ADORA2AGAAPKMTSHRCYP19A1 | |
| SCHEMBL7987743 | 0.79 | SCD (0.50) | GAAPKMTSHRSMN1; SMN2 | |
| SCHEMBL7975372 | 0.79 | ALDH1A1 (0.51) | ADORA2AGAAPKMTSHRALDH1A1 | |
| SCHEMBL7974026 | 0.79 | KDM4E (0.58) | ADORA2AGAAPKMTSHRALDH1A1 | |
| SCHEMBL7974168 | 0.79 | CDK9 (0.45) | GAAPKMTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL7987598 | 0.79 | RIOK2 (0.41) | CTRB1MC4RMC5RALDH1A1SMN1; SMN2 | |
| SCHEMBL7984239 | 0.79 | ADRA1D (0.52) | ADORA2AMEN1KMT2A | |
| SCHEMBL7984250 | 0.79 | PARP10 (0.53) | GAAPKMTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |