Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 4/20 | 0.48 |
| ▸ | AURKA | O14965 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | FLT1 | P17948 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | LYN | P07948 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987486 | 0.91 | KDM4E (0.48) | SMN1; SMN2AURKAKDRKDM4EHDAC1 | |
| SCHEMBL7974029 | 0.80 | ADORA3 (0.50) | ALDH1A1L3MBTL1KDM4EHDAC1 | |
| SCHEMBL7975241 | 0.80 | GAA (0.50) | SMN1; SMN2FLT3HDAC1GAA | |
| SCHEMBL7988029 | 0.78 | IDO1 (0.47) | SMN1; SMN2FLT3HDAC1BCHEGAA | |
| SCHEMBL7985255 | 0.77 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2L3MBTL1FLT3KDM4E | |
| SCHEMBL7988231 | 0.77 | NPC1 (0.47) | HDAC1 | |
| SCHEMBL7985682 | 0.76 | GAA (0.46) | ALDH1A1SMN1; SMN2KDM4EFLT1HDAC1 | |
| SCHEMBL7984687 | 0.75 | NR1H4 (0.52) | ALDH1A1 | |
| SCHEMBL7974581 | 0.74 | LMNA (0.51) | ALDH1A1SMN1; SMN2FLT3HDAC1GAA | |
| SCHEMBL7974265 | 0.74 | MCHR1 (0.47) | SMN1; SMN2L3MBTL1FLT3KDM4EHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |