Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.46 |
| ▸ | GBA1 | P04062 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 2/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 4/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | DHPS | P49366 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991669 | 0.89 | HDAC1 (0.38) | CDK9CYP11B2CYP11B1 | |
| SCHEMBL7985264 | 0.89 | CYP11B1 (0.41) | ALDH1A1CDK9CYP11B2CYP11B1MAOB | |
| SCHEMBL7989420 | 0.89 | MET (0.45) | ABCG2KDM4ECYP11B2CYP11B1DHPS | |
| SCHEMBL7985791 | 0.88 | CYP11B1 (0.40) | ABCG2ALDH1A1CDK9CYP11B2CYP11B1 | |
| SCHEMBL7988934 | 0.88 | CYP1A2 (0.47) | ABCG2KDM4EALDH1A1GRIN1GRIN2B | |
| SCHEMBL7988659 | 0.88 | P2RX7 (0.41) | ABCG2GRIN1GRIN2BPDE5ACYP11B2 | |
| SCHEMBL7974286 | 0.87 | DHPS (0.49) | ABCG2GBA1ALDH1A1CLK1DYRK1A | |
| SCHEMBL7991635 | 0.86 | IDO1 (0.37) | CDK9CYP11B2CYP11B1 | |
| SCHEMBL7988638 | 0.86 | MET (0.42) | KDM4EALDH1A1CDK9CYP11B2CYP11B1 | |
| SCHEMBL7985299 | 0.85 | CDK9 (0.39) | KDM4EALDH1A1CDK9CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |