Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986761 | 0.89 | HTT (0.36) | — | |
| SCHEMBL7937873 | 0.88 | HTR2A (0.41) | HRH3HTR2AHTR2CHTR7 | |
| SCHEMBL7938360 | 0.87 | POLB (0.36) | RAB9A | |
| SCHEMBL7969063 | 0.86 | CYP2D6 (0.42) | TSHR | |
| SCHEMBL7948263 | 0.84 | HPGD (0.36) | TSHRMMP3 | |
| SCHEMBL7947285 | 0.84 | HPGD (0.36) | TSHRMMP3 | |
| SCHEMBL7945107 | 0.84 | POLB (0.36) | RAB9A | |
| SCHEMBL7946077 | 0.83 | POLB (0.35) | RAB9AMMP3 | |
| SCHEMBL7969073 | 0.83 | MTNR1B (0.35) | TSHR | |
| SCHEMBL7947164 | 0.82 | PLA2G2A (0.37) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133387-A1 | INDOLE- 3 -GLYOXYLAMIDE DERIVATIVES FOR USE AS CALCIUM ION CHANNEL MODULATORS | LECTUS THERAPEUTICS LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |