SCHEMBL799841

SCHEMBL799841

CC(C)(C)c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.65
MAPT P10636 3/20 0.65
NPC1 O15118 3/20 0.65
HPGD P15428 2/20 0.65
ALDH1A1 P00352 2/20 0.65
MAPK1 P28482 1/20 0.65
LTA4H P09960 6/20 0.57
TSHR P16473 2/20 0.57
L3MBTL1 Q9Y468 2/20 0.53
TDP1 Q9NUW8 1/20 0.53
NR1H2 P55055 1/20 0.50
BAX Q07812 1/20 0.50
MAOA P21397 1/20 0.50
KDM4E B2RXH2 2/20 0.49
GAA P10253 1/20 0.49
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
NPSR1 Q6W5P4 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19392583 1.00 RAB9A (0.65) RAB9AMAPTNPC1HPGDALDH1A1
SCHEMBL13403329 0.94 MAPT (0.59) RAB9AMAPTNPC1HPGDALDH1A1
Diphenylether SCHEMBL16592512 0.93 LTA4H (0.60) RAB9AMAPTNPC1HPGDALDH1A1
SCHEMBL427816 0.90 RAB9A (0.77) RAB9AMAPTNPC1HPGDALDH1A1
SCHEMBL18118972 0.90 RAB9A (0.77) RAB9AMAPTNPC1HPGDALDH1A1
SCHEMBL127279 0.90 RAB9A (0.77) RAB9AMAPTNPC1HPGDALDH1A1
SCHEMBL19392589 0.88 RAB9A (0.53) RAB9AMAPTNPC1HPGDALDH1A1
SCHEMBL685353 0.88 RAB9A (0.53) RAB9AMAPTNPC1HPGDALDH1A1
SCHEMBL29377311 0.87 RAB9A (0.74) RAB9AMAPTNPC1HPGDALDH1A1
SCHEMBL686069 0.87 RAB9A (0.52) RAB9AMAPTNPC1HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 360 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228463-A1 SODIUM CHANNEL INHIBITORS AND METHODS OF DESIGNING SAME GENENTECH, INC. (US) 2024-07-11 US disclosed
US-20240228463-A1 SODIUM CHANNEL INHIBITORS AND METHODS OF DESIGNING SAME GENENTECH, INC. (US) 2024-07-11 US disclosed
US-12029111-B2 Oxygen heterocyclic compound, application thereof and electronic device using the same WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2024-07-02 US disclosed
US-12029111-B2 Oxygen heterocyclic compound, application thereof and electronic device using the same WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2024-07-02 US disclosed
US-20230382902-A1 MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2023-11-30 US disclosed
US-20230382902-A1 MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2023-11-30 US disclosed
US-20230330061-A1 ANTIMICROBIAL COMPOSITIONS, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF NATIONAL TAIWAN UNIVERSITY (TW) 2023-10-19 US disclosed
US-20230330061-A1 ANTIMICROBIAL COMPOSITIONS, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF NATIONAL TAIWAN UNIVERSITY (TW) 2023-10-19 US disclosed
US-20230286997-A1 Compounds for the Treatment of Cancer and Inflammatory Disease SHY Therapeutics LLC 2023-09-14 US disclosed
US-20230286997-A1 Compounds for the Treatment of Cancer and Inflammatory Disease SHY Therapeutics LLC 2023-09-14 US disclosed
CN-1088579-C Antiplaque oral composition COLGATE PALMOLIVE CO (US) 2002-08-07 CN disclosed
US-6395939-B1 CATALYTIC ETHERIFICATION AND CONDENSATION WITH COPPER CATALYSTS MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2002-05-28 US disclosed
WO-1999018057-A1 PREPARATION OF DIARYL ETHER BY CONDENSATION REACTIONS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1999-04-15 WO disclosed
CN-1200025-A Antiplaque oral composition COLGATE PALMOLIVE CO (US) 1998-11-25 CN disclosed
US-5814646-A TREATING THE PROGRESSION OF ALZHEIMER'S DISEASE, BRAIN DISORDERS ELI LILLY AND COMPANY (US) 1998-09-29 US disclosed
US-5432273-A Cyclizing a 5-(protected)oxy-5-(heterocyclic base)-3(S)-fluoro-1,2-(S)-pentanediol EMORY UNIVERSITY (US) 1995-07-11 US disclosed
US-5414078-A Preparation of 3'-substituted-2',3'-dideoxynucleosides and 2'-deoxynucleosides from acyclic, achiral precursors EMORY UNIVERSITY (US) 1995-05-09 US disclosed
WO-1992017485-A1 PREPARATION OF 3'-SUBSTITUTED-2',3'-DIDEOXYNUCLEOSIDES AND 2'-DEOXYNUCLEOSIDES FROM ACYCLIC, ACHIRAL PRECURSORS EMORY UNIVERSITY (US) 1992-10-15 WO disclosed
US-4066707-A METHOD FOR MANUFACTURE OF DIPHENOLS AND MONOALKYL ETHERS OF DIPHENOLS AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JA) 1978-01-03 US disclosed
US-3939113-A ANTHRAQUINONE DYES CIBA-GEIGY CORPORATION (US) 1976-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12029111-B2 Oxygen heterocyclic compound, application thereof and electronic device using the same AOC2, AOX1, TYR RAB9A 2784/4885MAPT 2401/4885NPC1 2611/4885
US-20230330061-A1 ANTIMICROBIAL COMPOSITIONS, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF FASN, NAAA, FPR3 RAB9A 2453/4885MAPT 1959/4885NPC1 643/4885
US-20230382902-A1 MONOACYLGLYCEROL LIPASE MODULATORS MGLL, LPL, LIPC RAB9A 905/4885MAPT 3815/4885NPC1 738/4885
US-20230286997-A1 Compounds for the Treatment of Cancer and Inflammatory Disease MAPK6, MAP3K6, MAPK4 RAB9A 2641/4885MAPT 2731/4885NPC1 2024/4885
US-20240228463-A1 SODIUM CHANNEL INHIBITORS AND METHODS OF DESIGNING SAME CACNA1I, CACNA1B, CACNA1C RAB9A 2580/4885MAPT 3123/4885NPC1 438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.