Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.43 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.43 |
| ▸ | P2RY12 known ✓ | Q9H244 | 1/20 | 0.41 |
| ▸ | P2RY4 known ✓ | P51582 | 1/20 | 0.39 |
| ▸ | P2RY2 known ✓ | P41231 | 1/20 | 0.38 |
| ▸ | P2RY6 known ✓ | Q15077 | 1/20 | 0.38 |
| ▸ | RAD51 | Q06609 | 10/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LTA | P01374 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8003381 | 1.00 | RAD51 (0.55) | RAD51CA1CA2CA9P2RY12 | |
| SCHEMBL8433654 | 0.87 | ENPP2 (0.43) | RAD51CA1CA2CA9PGR | |
| SCHEMBL8433673 | 0.87 | ENPP2 (0.43) | RAD51CA1CA2CA9PGR | |
| SCHEMBL9551824 | 0.86 | CA1 (0.43) | RAD51CA1CA2CA9PGR | |
| SCHEMBL8003406 | 0.86 | ENPP2 (0.42) | RAD51CA1CA2CA9PIN1 | |
| SCHEMBL9551821 | 0.86 | ENPP2 (0.42) | RAD51CA1CA2CA9PIN1 | |
| SCHEMBL8637919 | 0.85 | RAD51 (0.51) | RAD51CA1CA2CA9P2RY12 | |
| SCHEMBL8985671 | 0.85 | RAD51 (0.51) | RAD51CA1CA2CA9P2RY12 | |
| SCHEMBL30532269 | 0.84 | RAD51 (0.60) | RAD51CA1CA2CA9P2RY12 | |
| SCHEMBL893765 | 0.84 | RAD51 (0.60) | RAD51CA1CA2CA9P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4002480-A | CONTAINING A DINUCLEAR MEROCYANINE SENSITIZING DYE AND AN ANTIFOGGING AGENT | FUJI PHOTO FILM CO., LTD. (JA) | 1977-01-11 | — | — | US | claimed |
| EP-0647878-B1 | Silver halide photographic material | FUJI PHOTO FILM CO LTD (JP) | 2000-01-12 | — | — | EP | disclosed |
| EP-0532042-B1 | Silver halide photographic material | FUJI PHOTO FILM CO LTD (JP) | 1999-12-22 | — | — | EP | disclosed |
| US-5804362-A | GROUP VIII METAL, THIOSULFONATE | FUJI PHOTO FILM CO., LTD. (JP) | 1998-09-08 | — | — | US | disclosed |
| EP-0445627-B1 | Silver halide photographic light-sensitive materials | FUJI PHOTO FILM CO LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| EP-0474047-B1 | Silver halide emulsion | FUJI PHOTO FILM CO LTD (JP) | 1996-06-12 | — | — | EP | disclosed |
| EP-0383265-B1 | Method for forming color image | FUJI PHOTO FILM CO LTD (JP) | 1996-06-12 | — | — | EP | disclosed |
| US-5508161-A | SPECTRALLY SENSITIZED WITH A COMBINATION OF AT LEAST TWO J-BAND TYPE SENSITIZING DYES | FUJI PHOTO FILM CO., LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| US-5489505-A | ON A SUPPORT ATLEAST ONE SILVER HALIDE EMULSION AND ATLEAST ONE METHINE DYE; STORAGE STABILITY AND HIGH SENSITIVITY | FUJI PHOTO FILM CO., LTD. (JP) | 1996-02-06 | — | — | US | disclosed |
| EP-0230100-B1 | Light sensitive materials for lithographic printing plates | MITSUBISHI PAPER MILLS LTD (JP) | 1995-12-20 | — | — | EP | disclosed |
| EP-0383265-A2 | Method for forming color image | FUJI PHOTO FILM CO., LTD. (JP) | 1990-08-22 | — | — | EP | disclosed |
| EP-0369410-A2 | Silver halide photographic emulsion | FUJI PHOTO FILM CO., LTD. (JP) | 1990-05-23 | — | — | EP | disclosed |
| US-4770961-A | SILVER HALIDE EMULSIONS CONTAINING CYANINE DYES AS PHOTOSENSITIZERS; LASER OFFSET PRINTING | MITSUBISHI PAPER MILLS, LTD. (JP) | 1988-09-13 | — | — | US | disclosed |
| EP-0230100-A2 | Light sensitive materials for lithographic printing plates | MITSUBISHI PAPER MILLS, LTD. (JP) | 1987-07-29 | — | — | EP | disclosed |
| US-4677053-A | INFRARED SENSITIZING DYE; IMPROVED SHELF LIFE | YUJI MIHARA (JP) | 1987-06-30 | — | — | US | disclosed |
| US-4596767-A | Supersensitizing silver halide photographic material by incorporating therein an infrared sensitizing dye and an imino containing heterocyclic ring compound | FUJI PHOTO FILM CO., LTD. (JP) | 1986-06-24 | — | — | US | disclosed |
| US-4536473-A | Silver halide photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1985-08-20 | — | — | US | disclosed |
| EP-0138543-A2 | Silver halide photographic light sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1985-04-24 | — | — | EP | disclosed |
| US-4493889-A | RED SENSITIVITY | FUJI PHOTO FILM CO., LTD. (JP) | 1985-01-15 | — | — | US | disclosed |
| US-4002480-A | CONTAINING A DINUCLEAR MEROCYANINE SENSITIZING DYE AND AN ANTIFOGGING AGENT | FUJI PHOTO FILM CO., LTD. (JA) | 1977-01-11 | — | — | US | disclosed |