Decimemide

Decimemide

SCHEMBL80116

CCCCCCCCCCOc1c(OC)cc(C(N)=O)cc1OC

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.66
SMN1; SMN2 Q16637 1/20 0.66
BPTF Q12830 1/20 0.57
SMPD1 P17405 3/20 0.56
TSHR P16473 2/20 0.55
APOBEC3A P31941 1/20 0.53
HTT P42858 1/20 0.53
APOBEC3G Q9HC16 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15731815 0.91 TSHR (0.63) ALDH1A1SMN1; SMN2SMPD1TSHRHTT
SCHEMBL30937932 0.91 TSHR (0.63) ALDH1A1SMN1; SMN2SMPD1TSHRHTT
SCHEMBL79175 0.91 TSHR (0.63) ALDH1A1SMN1; SMN2SMPD1TSHRHTT
SCHEMBL30937931 0.91 TSHR (0.63) ALDH1A1SMN1; SMN2SMPD1TSHRHTT
SCHEMBL11435088 0.86 PLA2G2A (0.62) TSHR
SCHEMBL12431968 0.86 PLA2G2A (0.62) TSHR
SCHEMBL38650624 0.86 PLA2G2A (0.62) TSHR
SCHEMBL10822455 0.85 SLC6A5 (0.57) SMN1; SMN2SMPD1
Propionic Acid SCHEMBL21625678 0.85 TSHR (0.56) ALDH1A1SMN1; SMN2SMPD1TSHRHTT
SCHEMBL10822447 0.85 SLC6A5 (0.57) SMN1; SMN2SMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 922 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
EP-2560634-A1 NITRIC OXIDE RELEASING PRODRUGS OF THERAPEUTIC AGENTS Piramal Enterprises Limited (IN) 2013-02-27 EP claimed
US-20110263526-A1 Nitric Oxide Releasing Prodrugs of Therapeutic Agents PIRAMAL LIFE SCIENCES LIMITED (IN) 2011-10-27 US claimed
WO-2011132171-A1 NITRIC OXIDE RELEASING PRODRUGS OF THERAPEUTIC AGENTS PIRAMAL LIFE SCIENCES LIMITED (IN) 2011-10-27 WO claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101484152-A Therapeutic combination for painful medical conditions SANOL ARZNEI SCHWARZ GMBH (DE) 2009-07-15 CN claimed
EP-2026788-A1 THERAPEUTIC COMBINATION FOR PAINFUL MEDICAL CONDITIONS SCHWARZ PHARMA AG (DE) 2009-02-25 EP claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007141018-A1 THERAPEUTIC COMBINATION FOR PAINFUL MEDICAL CONDITIONS SCHWARZ PHARMA AG (DE) 2007-12-13 WO claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20070042969-A1 Combination therapy for pain in painful diabetic neuropathy SRZ PROPERTIES, INC. (US) 2007-02-22 US claimed
US-20070043120-A1 Therapeutic combination for painful medical conditions UCB PHARMA GMBH (DE) 2007-02-22 US claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
US-20260007660-A1 TREATMENT AND PREVENTION OF SLEEP DISORDERS PURDUE PHARMA L.P. (US) 2026-01-08 US disclosed
WO-1996040084-A1 COMPOSITIONS AND METHODS FOR USE OF PRESSURE SENSITIVE ADHESIVE TRANSDERMAL DEVICES CONTAINING A BIOADHESIVE HUMECTANT NOVEN PHARMACEUTICALS, INC. (US) 1996-12-19 WO disclosed
US-5446070-A Flexible, finite, bioadhesive, therapeutical agent in solid form NOVER PHARMACEUTICALS, INC. (US) 1995-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070042969-A1 Combination therapy for pain in painful diabetic neuropathy GRIN2B, GRIN2A, GRIN3A ALDH1A1 2350/4885SMN1; SMN2 488/4885BPTF 3966/4885
US-20260007660-A1 TREATMENT AND PREVENTION OF SLEEP DISORDERS CRY1, PER2, SLC6A1 ALDH1A1 126/4885SMN1; SMN2 360/4885BPTF 1383/4885
US-20110263526-A1 Nitric Oxide Releasing Prodrugs of Therapeutic Agents NOS2, NOS1, NOS3 ALDH1A1 204/4885SMN1; SMN2 2638/4885BPTF 4788/4885
US-20070043120-A1 Therapeutic combination for painful medical conditions PDE1B, CA2, CACNA1S ALDH1A1 2182/4885SMN1; SMN2 203/4885BPTF 3274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.