Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11974264 | 0.87 | ACHE (0.46) | ACHEHDAC4HDAC8POLBGAA | |
| SCHEMBL25620274 | 0.85 | ALDH1A1 (0.37) | ALDH1A1ACHETAS1R3TAS1R1POLB | |
| SCHEMBL17084605 | 0.85 | ALDH1A1 (0.33) | LMNAALDH1A1ACHETRPA1PTGS1 | |
| SCHEMBL12190511 | 0.85 | EIF4A3 (0.33) | LMNAACHETRPA1PTGS1CACNA1C | |
| SCHEMBL24344715 | 0.82 | CYP1A2 (0.38) | LMNAALDH1A1PTGS1AKR1B1ADRA2A | |
| SCHEMBL12062750 | 0.80 | MAPT (0.42) | ALDH1A1TRPA1PTGS1CACNA1CTAS1R3 | |
| SCHEMBL21667236 | 0.80 | SCN4A (0.33) | POLBGAAGFER | |
| SCHEMBL12180582 | 0.78 | LMNA (0.37) | LMNATRPA1PTGS1CACNA1CADRA2A | |
| SCHEMBL11210755 | 0.78 | PTGS1 (0.40) | LMNAALDH1A1ACHETRPA1PTGS1 | |
| SCHEMBL19362838 | 0.78 | ALDH1A1 (0.33) | ALDH1A1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787904-B2 | Phosphinated (2,6-dimethylphenyl ether) oligomer, preparation method thereof and cured product | CPC CORPORATION, TAIWAN (TW) | 2023-10-17 | — | — | US | disclosed |
| US-20230234963-A1 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | NOGRA PHARMA LIMITED (IE) | 2023-07-27 | — | — | US | disclosed |
| US-11708316-B2 | Hydrogenation of esters to alcohols in the presence of a Ru-PNN complex | BASF SE (DE) | 2023-07-25 | — | — | US | disclosed |
| US-11708316-B2 | Hydrogenation of esters to alcohols in the presence of a Ru-PNN complex | BASF SE (DE) | 2023-07-25 | — | — | US | disclosed |
| US-20230183219-A1 | CONDENSED SUBSTITUTED HYDROPYRROLES AS ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | VANDERBILT UNIVERSITY | 2023-06-15 | — | — | US | disclosed |
| US-11586060-B2 | Optical filter with light source | SOLUTIA CANADA INC. (CA) | 2023-02-21 | — | — | US | disclosed |
| WO-2022268525-A1 | HYDROGENATION OF ESTERS TO ALCOHOLS IN THE PRESENCE OF AN MN-PNN COMPLEX | BASF SE (DE) | 2022-12-29 | — | — | WO | disclosed |
| US-20220380279-A1 | HYDROGENATION OF ESTERS TO ALCOHOLS IN THE PRESENCE OF A RU-PNN COMPLEX | BASF SE (DE) | 2022-12-01 | — | — | US | disclosed |
| US-20210340321-A1 | PHOSPHINATED (2,6-DIMETHYLPHENYL ETHER) OLIGOMER, PREPARATION METHOD THEREOF AND CURED PRODUCT | CPC CORPORATION, TAIWAN (TW) | 2021-11-04 | — | — | US | disclosed |
| US-11124524-B2 | Diarylethene compounds and uses thereof | SOLUTIA CANADA INC. (US) | 2021-09-21 | — | — | US | disclosed |
| WO-2009092565-A1 | SUBSTITUTED TETRAHYDROIMIDAZOPYRIDINE COMPOUNDS AND THE USE THEREOF IN PHARMACEUTICALS | Grünenthal GmbH (DE) | 2009-07-30 | — | — | WO | disclosed |
| EP-2083009-A1 | Substituted tetrahydroimidazopyridine compounds and their use in medicine | Grünenthal GmbH (DE) | 2009-07-29 | — | — | EP | disclosed |
| US-20090186902-A1 | Substituted Tetrahydroimidazopyridine Compounds and the Use Thereof in the Treatment of Pain and Other Conditions | GRUENENTHAL GMBH (DE) | 2009-07-23 | — | — | US | disclosed |
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | DR. KARL THOMAE GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
| US-20090143381-A1 | MODULATORS OF ATP-BINDING CASSETTE-TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED | 2009-06-04 | — | — | US | disclosed |
| US-7498325-B2 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | KARL THOMAS GMBH (DE) | 2009-03-03 | — | — | US | disclosed |
| US-7498325-B2 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | KARL THOMAS GMBH (DE) | 2009-03-03 | — | — | US | disclosed |
| US-20080097078-A1 | Antibacterial activity against vancomycin-resistant bacteria | SHIONOGI & CO., LTD. (JP) | 2008-04-24 | — | — | US | disclosed |
| US-20080097078-A1 | Antibacterial activity against vancomycin-resistant bacteria | SHIONOGI & CO., LTD. (JP) | 2008-04-24 | — | — | US | disclosed |
| US-7256302-B2 | Catalyst ligand with groups on one or both of the benzene rings in a paracyclophane structure; high activity and selectivity for asymmetric reactions, facilitate chiral resolution | JOHNSON MATTHEY PLC (GB) | 2007-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | PTMS, CHRM1, SRMS | LMNA 1992/4885ALDH1A1 2929/4885ACHE 408/4885 |
| US-20230183219-A1 | CONDENSED SUBSTITUTED HYDROPYRROLES AS ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | CHRM3, CHRM2, CHRM4 | LMNA 4585/4885ALDH1A1 1756/4885ACHE 30/4885 |
| US-11124524-B2 | Diarylethene compounds and uses thereof | KCNH2, KCNH3, SCN2B | LMNA 2312/4885ALDH1A1 1014/4885ACHE 1217/4885 |
| US-20090186902-A1 | Substituted Tetrahydroimidazopyridine Compounds and the Use Thereof in the Treatment of Pain and Other Conditions | HRH4, TRPV1, QDPR | LMNA 1246/4885ALDH1A1 531/4885ACHE 48/4885 |
| US-20220380279-A1 | HYDROGENATION OF ESTERS TO ALCOHOLS IN THE PRESENCE OF A RU-PNN COMPLEX | ADH1A, PNN, ADH1C | LMNA 214/4885ALDH1A1 103/4885ACHE 3296/4885 |
| US-20230234963-A1 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | AHR, IL23R, IL2RA | LMNA 4543/4885ALDH1A1 774/4885ACHE 4531/4885 |
| US-20090143381-A1 | MODULATORS OF ATP-BINDING CASSETTE-TRANSPORTERS | CFTR, ABCB1, ABCC2 | LMNA 3826/4885ALDH1A1 1985/4885ACHE 4639/4885 |
| US-20080097078-A1 | Antibacterial activity against vancomycin-resistant bacteria | CSGALNACT1, MON2, NR2C2 | LMNA 4466/4885ALDH1A1 2289/4885ACHE 4329/4885 |
| US-11708316-B2 | Hydrogenation of esters to alcohols in the presence of a Ru-PNN complex | ADH1A, PNN, ADH1C | LMNA 214/4885ALDH1A1 103/4885ACHE 3296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.