SCHEMBL803076

SCHEMBL803076

CC(C)(C)C(=O)N1CCCC1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.48
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
ALDH1A1 P00352 5/20 0.43
HDAC6 Q9UBN7 2/20 0.39
ATM Q13315 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C19 P33261 1/20 0.38
YEATS4 O95619 1/20 0.37
MMP1 P03956 1/20 0.37
MMP2 P08253 1/20 0.37
MMP3 P08254 1/20 0.37
MMP9 P14780 1/20 0.37
HPGD P15428 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
HTT P42858 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7244910 0.97 ALDH1A1 (0.48) RIPK1MEN1KMT2AALDH1A1HDAC6
SCHEMBL803032 0.97 ALDH1A1 (0.48) RIPK1MEN1KMT2AALDH1A1HDAC6
SCHEMBL12339849 0.97 ALDH1A1 (0.48) RIPK1MEN1KMT2AALDH1A1HDAC6
SCHEMBL803077 0.94 RIPK1 (0.48) RIPK1MEN1KMT2AALDH1A1HDAC6
SCHEMBL673083 0.88
SCHEMBL10722471 0.88 MEN1 (0.52) RIPK1MEN1KMT2AALDH1A1HDAC6
SCHEMBL2676564 0.84 MEN1 (0.46) RIPK1MEN1KMT2AALDH1A1HDAC6
SCHEMBL25096322 0.83 CA2 (0.53) RIPK1MEN1KMT2AALDH1A1HDAC6
SCHEMBL24339467 0.82 HTT (0.52) RIPK1MEN1KMT2ACYP1A2HPGD
SCHEMBL8485188 0.81 FASN (0.44) MEN1KMT2AALDH1A1ATMCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 681 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109415508-A Full-size process for preparing polymer powders 西莫-戴顿有限责任公司 2019-03-01 CN claimed
CN-107207693-A Aqueous polyurethane dispersions 塔明克公司 2017-09-26 CN claimed
CN-106687540-A Low toxicity solvent system for polyamideimide and polyamide amic acid resin coating 富士胶片亨特化学制品美国有限公司 2017-05-17 CN claimed
US-20240216378-A1 TRIAZOLOPYRIMIDINE COMPOUNDS AND USES THEREOF NOVARTIS AG (CH) 2024-07-04 US disclosed
US-20240216378-A1 TRIAZOLOPYRIMIDINE COMPOUNDS AND USES THEREOF NOVARTIS AG (CH) 2024-07-04 US disclosed
WO-2024130342-A1 TRANSIENT RECEPTOR POTENTIAL VANILLOID 6 INHIBITORS UNIQUEST PTY LIMITED (AU) 2024-06-27 WO disclosed
US-11877464-B2 Organic light emitting element LG CHEM, LTD. (KR) 2024-01-16 US disclosed
US-11834419-B2 Compound, photoresist composition comprising same, photoresist pattern comprising same, and method for manufacturing photoresist pattern LG CHEM, LTD. (KR) 2023-12-05 US disclosed
US-20230364277-A1 E-SELECTIN TARGETING AGENTS GLYCOMIMETICS, INC. (US) 2023-11-16 US disclosed
US-20230329106-A1 ORGANIC LIGHT EMITTING ELEMENT LG CHEM, LTD. (KR) 2023-10-12 US disclosed
US-20230322732-A1 RIP1 Inhibitory Compounds and Methods for Making and Using the Same RIGEL PHARMACEUTICALS, INC. 2023-10-12 US disclosed
US-20070167428-A1 Thienopyrroles as antagonists of gnrh ASTRAZENECA AB (SE) 2007-07-19 US disclosed
US-20070167428-A1 Thienopyrroles as antagonists of gnrh ASTRAZENECA AB (SE) 2007-07-19 US disclosed
US-20070149538-A1 Diarylamine-Containing Compounds and Compositions, and their use as Modulators of C-Kit Receptors IRM LLC (BM) 2007-06-28 US disclosed
US-20070105852-A1 Thiophene and furan compounds ELI LILLY AND COMPANY 2007-05-10 US disclosed
US-20070099835-A1 Sustained release GLP-1 receptor modulators BRISTOL-MYERS SQUIBB COMPANY 2007-05-03 US disclosed
US-7202381-B2 Compounds as opioid receptor modulators JANSSEN PHARMACEUTICA, NV (BE) 2007-04-10 US disclosed
US-20070066573-A1 Pyrrole and pyrazole derivatives as potentiators of glutamate receptors ELI LILLY AND COMPANY 2007-03-22 US disclosed
US-20070004675-A1 Inhibitors of VEGF receptor and HGF receptor signaling METHYLGENE, INC. 2007-01-04 US disclosed
US-20070004675-A1 Inhibitors of VEGF receptor and HGF receptor signaling METHYLGENE, INC. 2007-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329106-A1 ORGANIC LIGHT EMITTING ELEMENT PPA1, PPOX, APRT RIPK1 3328/4885MEN1 1791/4885KMT2A 3533/4885
US-20070004675-A1 Inhibitors of VEGF receptor and HGF receptor signaling HGF, MET, FLT1 RIPK1 1154/4885MEN1 3655/4885KMT2A 3391/4885
US-11834419-B2 Compound, photoresist composition comprising same, photoresist pattern comprising same, and method for manufacturing photoresist pattern PPOX, SETD7, CRY1 RIPK1 2713/4885MEN1 1277/4885KMT2A 567/4885
US-11877464-B2 Organic light emitting element CACNA2D4, CYBA, L1CAM RIPK1 3266/4885MEN1 1889/4885KMT2A 4166/4885
US-20230322732-A1 RIP1 Inhibitory Compounds and Methods for Making and Using the Same RIPK1, RIPK2, RIPK3 RIPK1 1/4885MEN1 2540/4885KMT2A 3696/4885
US-20070099835-A1 Sustained release GLP-1 receptor modulators GLP1R, GIPR, GRPR RIPK1 1807/4885MEN1 1181/4885KMT2A 4088/4885
US-20230364277-A1 E-SELECTIN TARGETING AGENTS SELE, SELPLG, SELP RIPK1 3522/4885MEN1 2033/4885KMT2A 4068/4885
US-20070167428-A1 Thienopyrroles as antagonists of gnrh GNRHR, PRLHR, TRHR RIPK1 2183/4885MEN1 923/4885KMT2A 1902/4885
US-20240216378-A1 TRIAZOLOPYRIMIDINE COMPOUNDS AND USES THEREOF EZH2, DOT1L, EED RIPK1 2297/4885MEN1 1351/4885KMT2A 27/4885
US-20070149538-A1 Diarylamine-Containing Compounds and Compositions, and their use as Modulators of C-Kit Receptors KIT, PRKCH, PRKCE RIPK1 2266/4885MEN1 2421/4885KMT2A 646/4885
US-20070105852-A1 Thiophene and furan compounds PSEN2, PSEN1, TPMT RIPK1 4016/4885MEN1 3839/4885KMT2A 3101/4885
US-20070066573-A1 Pyrrole and pyrazole derivatives as potentiators of glutamate receptors GRIN1, GRIN3A, GRIK5 RIPK1 793/4885MEN1 4720/4885KMT2A 3400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.