Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042803 | 0.80 | MAPK8 (0.46) | ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL8044870 | 0.78 | ALDH1A1 (0.41) | LOXL2ALDH1A1LMNATP53HTT | |
| SCHEMBL8045845 | 0.78 | TRPM8 (0.32) | LOXL2 | |
| SCHEMBL8048224 | 0.77 | RAB9A (0.39) | LOXL2ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL8045225 | 0.76 | KMT2A (0.46) | ALDH1A1LMNATP53HTTSMN1; SMN2 | |
| SCHEMBL8045587 | 0.76 | — | — | |
| SCHEMBL8042935 | 0.76 | NPC1 (0.40) | SMN1; SMN2GRM5 | |
| SCHEMBL8034002 | 0.76 | LOXL2 (0.32) | LOXL2 | |
| SCHEMBL8047833 | 0.76 | NPC1 (0.40) | ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL8032788 | 0.75 | PTGS2 (0.33) | LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |