SCHEMBL80409

SCHEMBL80409

Brc1ccccc1C1(C2(c3ccccc3Br)N=C(c3ccccc3)C(c3ccccc3)=N2)N=C(c2ccccc2)C(c2ccccc2)=N1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
MAPK1 P28482 4/20 0.40
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
RAB9A P51151 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
TP53 P04637 1/20 0.33
MAPT P10636 1/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CRHBP P24387 1/20 0.32
CRHR2 Q13324 1/20 0.32
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32
TSHR P16473 1/20 0.31
KMT2A Q03164 1/20 0.31
NPC1 O15118 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29469982 1.00 ALDH1A1 (0.40) ALDH1A1MAPK1HTR2AHTR2CRAB9A
SCHEMBL491334 0.85 HTR2A (0.31) HTR2AHTR2C
SCHEMBL2496616 0.82 CHRM1 (0.38) ALDH1A1MAPK1RAB9ASMN1; SMN2TP53
SCHEMBL2233605 0.78
SCHEMBL8665932 0.78 IDO1 (0.37) ALDH1A1MAPK1SMN1; SMN2MAPTTSHR
SCHEMBL155813 0.76 ALDH1A1 (0.34) ALDH1A1MAPK1RAB9ASMN1; SMN2NFKB1
SCHEMBL82274 0.76 TAAR1 (0.40) ALDH1A1RAB9ASMN1; SMN2TP53L3MBTL1
SCHEMBL81799 0.76 ALDH1A1 (0.38) ALDH1A1RAB9ASMN1; SMN2TP53MAPT
SCHEMBL30987503 0.76 ALDH1A1 (0.34) ALDH1A1MAPK1RAB9ASMN1; SMN2NFKB1
SCHEMBL29362744 0.76 TAAR1 (0.40) ALDH1A1RAB9ASMN1; SMN2TP53L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1266 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0520364-B1 Photopolymerizable composition FUJI PHOTO FILM CO LTD (JP) 1997-09-17 EP claimed
EP-0377321-B1 Photopolymerizable composition FUJI PHOTO FILM CO LTD (JP) 1995-03-22 EP claimed
US-5385807-A Photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1995-01-31 US claimed
EP-0520364-A1 Photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1992-12-30 EP claimed
US-5049481-A Merocyanine compound FUJI PHOTO FILM CO., LTD. (JP) 1991-09-17 US claimed
US-4985470-A Three component photoinitiator system, printing plates, photoresists, inks, paints, adhesives MITSUBISHI KASEI CORPORATION (JP) 1991-01-15 US claimed
EP-0377321-A2 Photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1990-07-11 EP claimed
EP-0138187-B1 PHOTOPOLYMERIZABLE COMPOSITION MITSUBISHI KASEI CORPORATION (JP) 1989-01-11 EP claimed
US-4594310-A Photopolymerizable composition comprising tertiary aromatic amine and hexaarylbiimazole initiators MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) 1986-06-10 US claimed
EP-0107792-B1 PHOTOPOLYMERIZABLE COMPOSITIONS MITSUBISHI KASEI CORPORATION (JP) 1985-12-27 EP claimed
EP-0138187-A2 Photopolymerizable composition MITSUBISHI KASEI CORPORATION (JP) 1985-04-24 EP claimed
EP-0107792-A1 Photopolymerizable compositions MITSUBISHI KASEI CORPORATION (JP) 1984-05-09 EP claimed
US-12637600-B2 Photocurable composition, cured product of same, photofusible resin composition and adhesive set RESONAC CORPORATION (JP) 2026-05-26 US disclosed
US-20260132243-A1 THERMOSETTING COMPOSITION AND CURED PRODUCT THEREOF, PHOTOMELTABLE COMPOSITION, AND STRUCTURAL BODY PRODUCTION METHOD RESONAC CORP (JP) 2026-05-14 US disclosed
EP-4410859-B1 THERMOSETTING COMPOSITION AND CURED PRODUCT THEREOF, PHOTO-MELTABLE COMPOSITION, AND STRUCTURAL BODY PRODUCTION METHOD RESONAC CORP (JP) 2026-04-29 EP disclosed
US-12565600-B2 Photopolymerizable composition, cured substance, and optical member FUJIFILM CORPORATION (JP) 2026-03-03 US disclosed
US-4332884-A USING A DIOXIME CHELATING AGENT RICOH CO., LTD. (JP) 1982-06-01 US disclosed
US-4315068-A CONTAINING A COBALT-AMMINE COMPLEX AND A DIOXIME OR A BISIMIDAZOLIN-3-ONE CHELATING AGENT; STABILITY; COLOR DILMS RICOH CO., LTD. (JP) 1982-02-09 US disclosed
US-4306014-A AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM RICOH CO., LTD. (JP) 1981-12-15 US disclosed
US-4017313-A Photosensitive composition containing a leuco dye, a photosensitizer, an aromatic aldehyde and a secondary or tertiary amine and the use thereof in a direct-print process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637600-B2 Photocurable composition, cured product of same, photofusible resin composition and adhesive set ESD, CDH1, ASH2L ALDH1A1 95/4885MAPK1 4214/4885HTR2A 2156/4885
US-12565600-B2 Photopolymerizable composition, cured substance, and optical member PRXL2A, MLX, NR0B1 ALDH1A1 1098/4885MAPK1 1269/4885HTR2A 866/4885
US-20260132243-A1 THERMOSETTING COMPOSITION AND CURED PRODUCT THEREOF, PHOTOMELTABLE COMPOSITION, AND STRUCTURAL BODY PRODUCTION METHOD RER1, OXTR, MAP1LC3A ALDH1A1 379/4885MAPK1 1074/4885HTR2A 2719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.