Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.63 |
| ▸ | QPCT | Q16769 | 6/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PRKCI | P41743 | 1/20 | 0.51 |
| ▸ | SOD1 | P00441 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10771358 | 0.94 | TBXAS1 (0.67) | TBXAS1QPCTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL46694 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL14119641 | 0.86 | QPCT (0.56) | TBXAS1QPCTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5878941 | 0.84 | TBXAS1 (0.63) | TBXAS1QPCTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19786259 | 0.83 | TBXAS1 (0.68) | TBXAS1QPCTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20966334 | 0.82 | TBXAS1 (0.65) | TBXAS1QPCTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12803431 | 0.81 | TBXAS1 (0.60) | TBXAS1QPCTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8365568 | 0.81 | TBXAS1 (0.59) | TBXAS1QPCTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9777196 | 0.80 | TBXAS1 (0.85) | TBXAS1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL937596 | 0.80 | TBXAS1 (0.95) | TBXAS1PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 299 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476803-B | Amine compositions useful for making polyurethane foams | 赢创运营有限公司 | 2022-04-12 | — | — | CN | claimed |
| EP-1971600-B1 | ISOXAZOLE DERIVATIVES AND USE THEREOF | SK BIOPHARMACEUTICALS CO LTD (KR) | 2013-08-21 | — | — | EP | claimed |
| US-20090131336-A1 | Isoxazole Derivatives and Use Thereof | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2009-05-21 | — | — | US | claimed |
| US-20040063773-A1 | Pyrrole substituted 2-indolinone protein kinase inhibitors | SUGEN, INC. & PHARMACIA & UPJOHN CO. | 2004-04-01 | — | — | US | claimed |
| EP-1255752-A2 | PYRROLE SUBSTITUTED 2-INDOLINONE PROTEIN KINASE INHIBITORS | Sugen, Inc. (US) | 2002-11-13 | — | — | EP | claimed |
| US-20020156292-A1 | Pyrrole substituted 2-indolinone protein kinase inhibitors | PHARMACIA & UPJOHN COMPANY LLC | 2002-10-24 | — | — | US | claimed |
| WO-2001060814-A2 | PYRROLE SUBSTITUTED 2-INDOLINONE PROTEIN KINASE INHIBITORS | SUGEN, INC. (US) | 2001-08-23 | — | — | WO | claimed |
| US-20250161307-A1 | PYRAZOLOPYRIMIDINES AS MODULATORS OF SPERMINE OXIDASE | JANSSEN PHARMACEUTICA NV (BE) | 2025-05-22 | — | — | US | disclosed |
| EP-4469454-A1 | PYRAZOLOPYRIMIDINES AS MODULATORS OF SPERMINE OXIDASE | Janssen Pharmaceutica NV (BE) | 2024-12-04 | — | — | EP | disclosed |
| US-20240208934-A1 | ULK1/2 INHIBITORS AND THEIR USE THEREOF | LIFEARC (GB) | 2024-06-27 | — | — | US | disclosed |
| US-20240208934-A1 | ULK1/2 INHIBITORS AND THEIR USE THEREOF | LIFEARC (GB) | 2024-06-27 | — | — | US | disclosed |
| WO-2023183887-A2 | COMPOSITIONS FOR AND METHODS OF MODULATING RNA STABILITY | DUKE UNIVERSITY (US) | 2023-09-28 | — | — | WO | disclosed |
| CN-114478318-B | Dinitrile isophorone derivative, preparation method and application thereof | 河南应用技术职业学院 | 2023-08-18 | — | — | CN | disclosed |
| WO-2002014354-A1 | WATER SOLUBLE THIAZOLYL PEPTIDE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-02-21 | — | — | WO | disclosed |
| WO-1993013075-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | THE BOOTS COMPANY PLC (GB) | 1993-07-08 | — | — | WO | disclosed |
| US-5081131-A | Omega-((hetero)alkyl)benz(cd)-indol-2-amines | AMERICAN CYANAMID COMPANY (US) | 1992-01-14 | — | — | US | disclosed |
| EP-0230035-A2 | Omega-[(hetero)alkyl]benz[cd]indol-2-amines | AMERICAN CYANAMID COMPANY (US) | 1987-07-29 | — | — | EP | disclosed |
| US-4450277-A | Preparation of 1-substituted imidazoles | BASF AKTIENGESELLSCHAFT (DE) | 1984-05-22 | — | — | US | disclosed |
| EP-0026908-B1 | PROCESS FOR PREPARING 1-SUBSTITUTED IMIDAZOLES | BASF Aktiengesellschaft (DE) | 1983-06-22 | — | — | EP | disclosed |
| EP-0026908-A1 | Process for preparing 1-substituted imidazoles | BASF Aktiengesellschaft (DE) | 1981-04-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208934-A1 | ULK1/2 INHIBITORS AND THEIR USE THEREOF | ULK1, ULK2, ULK3 | TBXAS1 3253/4885QPCT 3645/4885CYP1A2 3776/4885 |
| US-20250161307-A1 | PYRAZOLOPYRIMIDINES AS MODULATORS OF SPERMINE OXIDASE | SMOX, SRM, SMS | TBXAS1 274/4885QPCT 2388/4885CYP1A2 423/4885 |
| US-20040063773-A1 | Pyrrole substituted 2-indolinone protein kinase inhibitors | PDPK1, MAP3K20, PLK2 | TBXAS1 1776/4885QPCT 1290/4885CYP1A2 3417/4885 |
| US-20090131336-A1 | Isoxazole Derivatives and Use Thereof | WNT3A, WNT1, WNT3 | TBXAS1 183/4885QPCT 4052/4885CYP1A2 413/4885 |
| US-20020156292-A1 | Pyrrole substituted 2-indolinone protein kinase inhibitors | PDPK1, MAP3K20, PLK2 | TBXAS1 1776/4885QPCT 1290/4885CYP1A2 3417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.