Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094492 | 0.84 | MAPK8 (0.41) | ALDH1A1KDM4EMAPK8MAPK9MAPK10 | |
| SCHEMBL7233873 | 0.81 | MAPK8 (0.54) | SMN1; SMN2LMNAL3MBTL1KMT2AMAPT | |
| SCHEMBL8069562 | 0.81 | MAPK8 (0.47) | LMNAKMT2AMAPTMEN1RAB9A | |
| SCHEMBL8104093 | 0.80 | KMT2A (0.49) | LMNAL3MBTL1KMT2AMAPTMEN1 | |
| SCHEMBL7232438 | 0.78 | GLS (0.43) | SMN1; SMN2LMNAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL7998311 | 0.77 | GLS (0.44) | SMN1; SMN2L3MBTL1MAPTALDH1A1RAB9A | |
| SCHEMBL7735892 | 0.76 | RAB9A (0.46) | SMN1; SMN2L3MBTL1KMT2AMAPTMEN1 | |
| SCHEMBL8094494 | 0.75 | MAPK8 (0.44) | LMNAMAPTALDH1A1RAB9AMAPK8 | |
| SCHEMBL7994626 | 0.74 | GLS (0.42) | SMN1; SMN2L3MBTL1MAPTALDH1A1RAB9A | |
| SCHEMBL7997967 | 0.70 | KDM4E (0.41) | SMN1; SMN2LMNAMAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991631-A1 | SUBSTITUTED AMINOHETEROCYCLYLAMIDES | Bayer Aktiengesellschaft (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000375-A1 | SUBSTITUTED AMINOHETEROCYCLYLAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-07 | — | — | WO | disclosed |