Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | BMP1 | P13497 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8092409 | 0.87 | HSD11B1 (0.47) | CA12CA9RAB9ASMN1; SMN2CA1 | |
| SCHEMBL8079204 | 0.85 | CNR2 (0.47) | ALDH1A1CA12CA9NPC1RAB9A | |
| SCHEMBL8092540 | 0.82 | TAS2R14 (0.50) | ALDH1A1NPC1RAB9ABMP1 | |
| SCHEMBL8079261 | 0.80 | HSD11B1 (0.45) | CA12CA9KCNH2KMT2AMEN1 | |
| SCHEMBL8090675 | 0.75 | TAAR1 (0.43) | CA12CA9RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL8092470 | 0.75 | TAS2R14 (0.49) | BMP1 | |
| SCHEMBL8087752 | 0.74 | CES2 (0.43) | CA12CA9NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8087638 | 0.74 | TAS2R14 (0.50) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8087708 | 0.74 | TRPM8 (0.45) | ALDH1A1RAB9ASMN1; SMN2KCNH2KMT2A | |
| SCHEMBL6806990 | 0.74 | PKM (0.52) | ALDH1A1CA12CA9SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047670-A1 | AMINOSULPHONYLBENZAMIDE DERIVATIVES AS MODULATORS OF THE ACTIVITY OF NEURONAL CALCIUM CHANNELS | ELI LILLY AND COMPANY LIMITED (GB) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999036398-A1 | AMINOSULPHONYLBENZAMIDE DERIVATIVES AS MODULATORS OF THE ACTIVITY OF NEURONAL CALCIUM CHANNELS | ELI LILLY AND COMPANY LIMITED (GB) | 1999-07-22 | — | — | WO | disclosed |