SCHEMBL810837

SCHEMBL810837

Cc1ccc(S(=O)(=O)N(C)C2CCCCC2N)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.51
HTR2C P28335 3/20 0.51
SIGMAR1 Q99720 1/20 0.49
ALDH1A1 P00352 3/20 0.49
KMT2A Q03164 2/20 0.49
KDM4E B2RXH2 1/20 0.49
MEN1 O00255 1/20 0.49
C5AR1 P21730 1/20 0.45
CA12 O43570 1/20 0.44
CA9 Q16790 1/20 0.44
MAPT P10636 1/20 0.44
MCOLN3 Q8TDD5 1/20 0.44
LMNA P02545 3/20 0.43
GAA P10253 1/20 0.43
CYP3A4 P08684 1/20 0.42
TSHR P16473 1/20 0.42
AGER Q15109 1/20 0.41
POLB P06746 1/20 0.41
CNR1 P21554 2/20 0.40
CNR2 P34972 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28010137 0.86 ALDH1A1 (0.43) HTR2AHTR2CALDH1A1KMT2AMEN1
SCHEMBL17481682 0.78 GPR55 (0.53) HTR2AHTR2CSIGMAR1ALDH1A1KMT2A
SCHEMBL16057026 0.78 GPR55 (0.53) HTR2AHTR2CSIGMAR1ALDH1A1KMT2A
SCHEMBL11456153 0.78 POLB (0.44) HTR2AHTR2CALDH1A1KMT2AKDM4E
SCHEMBL11456154 0.78 POLB (0.44) HTR2AHTR2CALDH1A1KMT2AKDM4E
SCHEMBL9303072 0.78 ALDH1A1 (0.73) HTR2AHTR2CALDH1A1KMT2AKDM4E
SCHEMBL887361 0.75 HTR2A (0.37) HTR2AHTR2CALDH1A1KMT2AMEN1
SCHEMBL9114934 0.74 STAT5B (0.39) ALDH1A1KMT2AMEN1LMNACYP3A4
SCHEMBL4367433 0.74 STAT5B (0.39) ALDH1A1KMT2AMEN1LMNACYP3A4
SCHEMBL14062319 0.74 ACHE (0.49) HTR2AHTR2CALDH1A1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2399895-B1 Process for producing optically active aliphatic fluoroalcohol KANTO KAGAKU (JP) 2018-08-08 EP disclosed
US-9162934-B2 Process for producing optically active alcohol KANTO KAGAKU KABUSHIKI KAISHA (JP) 2015-10-20 US disclosed
EP-2394977-B1 Process for producing optically active alcohol KANTO KAGAKU (JP) 2014-01-08 EP disclosed
US-8558033-B2 Process for producing optically active aliphatic fluoroalcohol KANTO KAGAKU KABUSHIKI KAISHA (JP) 2013-10-15 US disclosed
US-20110319671-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE ALIPHATIC FLUOROALCOHOL KANTO KAGAKU KABUSHIKI KAISHA (JP) 2011-12-29 US disclosed
EP-2399895-A2 Process for producing optically active aliphatic fluoroalcohol Kanto Kagaku Kabushiki Kaisha (JP) 2011-12-28 EP disclosed
EP-2394977-A1 Process for producing optically active alcohol Kanto Kagaku Kabushiki Kaisha (JP) 2011-12-14 EP disclosed
US-20110282077-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL KANTO KAGAKU KABUSHIKI KAISHA (JP) 2011-11-17 US disclosed
US-7268250-B2 Process for producing optically active compound KANTO KAGAKU KABUSHIKI KAISHA (JP) 2007-09-11 US disclosed
EP-1439159-B1 Process for producing optically active compound KANTO KAGAKU (JP) 2007-06-20 EP disclosed
US-20040176616-A1 Process for producing optically active compound KANTO KAGAKU KABUSHIKI KAISHA 2004-09-09 US disclosed
EP-1439159-A1 Process for producing optically active compound Kanto Kagaku Kabushiki Kaisha (JP) 2004-07-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040176616-A1 Process for producing optically active compound OSTC, NPEPPS, PPOX HTR2A 3671/4885HTR2C 3757/4885SIGMAR1 2485/4885
US-20110282077-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL ADH1A, ADH1C, ADH5 HTR2A 1843/4885HTR2C 2987/4885SIGMAR1 2025/4885
US-20110319671-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE ALIPHATIC FLUOROALCOHOL ADH1A, ADH1C, ADH5 HTR2A 4290/4885HTR2C 4335/4885SIGMAR1 805/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.