SCHEMBL816928

SCHEMBL816928

[c]1cccc2ccc3c(c12)-c1ccccc1C3

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.37
KDM4E B2RXH2 2/20 0.36
NPC1 O15118 2/20 0.36
MAPT P10636 2/20 0.36
RAB9A P51151 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
HPGD P15428 1/20 0.36
CYP3A4 P08684 3/20 0.36
TSHR P16473 2/20 0.36
MEN1 O00255 1/20 0.36
TP53 P04637 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
PKM P14618 1/20 0.36
MAPK1 P28482 1/20 0.36
CYP2C19 P33261 1/20 0.36
KMT2A Q03164 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17063439 0.80 ALDH1A1 (0.35) MAPTALDH1A1CYP3A4TSHRHSD17B10
SCHEMBL17063435 0.79 MAOA (0.36) MAOAKDM4ENPC1MAPTRAB9A
SCHEMBL816270 0.78 NPC1 (0.39) MAOAKDM4ENPC1MAPTRAB9A
SCHEMBL814655 0.77 PNMT (0.40) MAOAKDM4ENPC1MAPTRAB9A
SCHEMBL813886 0.76 KDM4E (0.34) MAOAKDM4ENPC1MAPTRAB9A
SCHEMBL29216529 0.73 MAOA (0.37) MAOAKDM4ENPC1MAPTRAB9A
SCHEMBL30403300 0.73 MAOA (0.56) MAOAKDM4ENPC1MAPTRAB9A
SCHEMBL815115 0.73 PNMT (0.37) MAOAKDM4ENPC1MAPTRAB9A
SCHEMBL28701351 0.73 MAPK8 (0.35) MAOAKDM4ENPC1MAPTRAB9A
SCHEMBL867598 0.73 DNMT1 (0.44) MAOAKDM4ENPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399199-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS Reuter Chemische Apparatebau e.K. (DE) 2024-07-17 EP claimed
EP-4399200-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS Mitsubishi Gas Chemical Company, Inc. (JP) 2024-07-17 EP claimed
CN-118043298-A (Hetero) aryl-substituted bisphenol compound and thermoplastic resin 罗伊特化学仪器制造公司 2024-05-14 CN claimed
CN-117940399-A Heteroaryl or aryl substituted bisphenol compounds and thermoplastic resins 三菱瓦斯化学株式会社 2024-04-26 CN claimed
WO-2023036868-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS REUTER CHEMISCHE APPARATEBAU E.K. (DE) 2023-03-16 WO claimed
WO-2023038156-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-03-16 WO claimed
US-20210328150-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, ORGANIC ELECTROLUMINESCENT MATERIAL COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-10-21 US claimed
CN-113493422-A Organic electroluminescent compound, organic electroluminescent material comprising same, and organic electroluminescent device 罗门哈斯电子材料韩国有限公司 2021-10-12 CN claimed
US-10038152-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-07-31 US claimed
EP-1690847-B1 pi-conjugated compound having cardo structure, process for the preparation thereof and use thereof TOSOH CORP (JP) 2016-06-22 EP claimed
WO-2011115378-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2011-09-22 WO claimed
US-20060186797-A1 Pi-conjugated compound having cardo structure, process for preparing same and use of same TOSOH CORPORATION (JP) 2006-08-24 US claimed
EP-1690847-A1 pi-Conjugated compound having cardo structure, process for the preparation thereof and use thereof Tosoh Corporation (JP) 2006-08-16 EP claimed
EP-4399199-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS Reuter Chemische Apparatebau e.K. (DE) 2024-07-17 EP disclosed
EP-4399200-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS Mitsubishi Gas Chemical Company, Inc. (JP) 2024-07-17 EP disclosed
US-20240188424-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2024-06-06 US disclosed
US-20060160968-A1 Process for producing substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-07-20 US disclosed
US-20060160967-A1 Halogen substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-07-20 US disclosed
WO-2006065844-A2 PROCESS FOR PRODUCING SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed
WO-2006065843-A2 HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10038152-B2 Organic light-emitting element NFE2L2, EML4, LEF1 MAOA 251/4885KDM4E 2414/4885NPC1 2706/4885
US-20060186797-A1 Pi-conjugated compound having cardo structure, process for preparing same and use of same ARL1, TERB1, LEO1 MAOA 2200/4885KDM4E 4538/4885NPC1 1402/4885
US-20240188424-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, L1CAM, EPCAM MAOA 653/4885KDM4E 2913/4885NPC1 3496/4885
US-20060160967-A1 Halogen substituted metallocene compounds for olefin polymerization OR10J3, ZRANB2, SLC39A3 MAOA 1918/4885KDM4E 3672/4885NPC1 2361/4885
US-20060160968-A1 Process for producing substituted metallocene compounds for olefin polymerization OSBP, OSBPL3, OSBP2 MAOA 1197/4885KDM4E 3408/4885NPC1 950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.