SCHEMBL814655

SCHEMBL814655

[c]1cccc2ccc3c(c12)Cc1ccccc1-3

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.40
NPC1 O15118 4/20 0.36
RAB9A P51151 4/20 0.36
KDM4E B2RXH2 3/20 0.36
MAPT P10636 3/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
ALDH1A1 P00352 2/20 0.36
LMNA P02545 1/20 0.36
HPGD P15428 1/20 0.36
PGR P06401 1/20 0.35
HTR7 P34969 2/20 0.33
HTR2B P41595 2/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
MAOA P21397 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
CYP3A4 P08684 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL815115 0.89 PNMT (0.37) PNMTNPC1RAB9AKDM4EMAPT
SCHEMBL17063412 0.79 PNMT (0.39) PNMTNPC1RAB9AKDM4EMAPT
SCHEMBL816928 0.77 MAOA (0.37) NPC1RAB9AKDM4EMAPTSMN1; SMN2
SCHEMBL816270 0.75 NPC1 (0.39) NPC1RAB9AKDM4EMAPTSMN1; SMN2
SCHEMBL285402 0.73 CA1 (0.40) PNMTNPC1RAB9AKDM4EMAPT
SCHEMBL22263591 0.73 PNMT (0.57) PNMTNPC1RAB9AKDM4EMAPT
SCHEMBL29197348 0.73 MAOA (0.47) NPC1RAB9AKDM4ESMN1; SMN2LMNA
Benzo(A)Fluorene SCHEMBL150250 0.73 CA1 (0.46) PNMTNPC1RAB9AKDM4EMAPT
SCHEMBL28697678 0.73 CA1 (0.41) PNMTNPC1RAB9AKDM4EMAPT
Benzo(A)Fluorene SCHEMBL29432662 0.73 CA1 (0.46) PNMTNPC1RAB9AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210328150-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, ORGANIC ELECTROLUMINESCENT MATERIAL COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-10-21 US claimed
CN-113493422-A Organic electroluminescent compound, organic electroluminescent material comprising same, and organic electroluminescent device 罗门哈斯电子材料韩国有限公司 2021-10-12 CN claimed
US-10038152-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-07-31 US claimed
EP-4399200-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS Mitsubishi Gas Chemical Company, Inc. (JP) 2024-07-17 EP disclosed
EP-4399199-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS Reuter Chemische Apparatebau e.K. (DE) 2024-07-17 EP disclosed
US-20240188424-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2024-06-06 US disclosed
US-20240174694-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2024-05-30 US disclosed
CN-117903127-A Organic electroluminescent compound, various host materials, and organic electroluminescent device comprising the same 罗门哈斯电子材料韩国有限公司 2024-04-19 CN disclosed
US-20240130230-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2024-04-18 US disclosed
US-11963439-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2024-04-16 US disclosed
US-20240114778-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2024-04-04 US disclosed
US-20070135595-A1 Halogen substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS, INC. 2007-06-14 US disclosed
US-20070135594-A1 Halogen substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
US-20070135623-A1 Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
US-20070135596-A1 Preparation of substituted bridged indenyl and related ligands EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
US-20060183874-A1 Halogen substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-08-17 US disclosed
US-20060160967-A1 Halogen substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-07-20 US disclosed
US-20060160968-A1 Process for producing substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-07-20 US disclosed
EP-0832883-B1 Tetrahydrobenzo(a)fluorene compounds and methods of use LILLY CO ELI (US) 2002-04-03 EP disclosed
EP-0832883-A1 Tetrahydrobenzo(a)fluorene compounds and methods of use ELI LILLY AND COMPANY (US) 1998-04-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240174694-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME PIEZO1, SOD1, NECTIN4 PNMT 1175/4885NPC1 2460/4885RAB9A 1755/4885
US-10038152-B2 Organic light-emitting element NFE2L2, EML4, LEF1 PNMT 2304/4885NPC1 2706/4885RAB9A 4270/4885
US-20070135623-A1 Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization OPRM1, POLM, AP1M1 PNMT 64/4885NPC1 3804/4885RAB9A 4548/4885
US-20060183874-A1 Halogen substituted metallocene compounds for olefin polymerization B2M, CDYL, MLX PNMT 3613/4885NPC1 2321/4885RAB9A 4002/4885
US-11963439-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same OR10J3, VDAC2, ICOSLG PNMT 185/4885NPC1 2766/4885RAB9A 1594/4885
US-20070135596-A1 Preparation of substituted bridged indenyl and related ligands SP1, TTL, TTLL12 PNMT 4341/4885NPC1 1782/4885RAB9A 3323/4885
US-20070135594-A1 Halogen substituted metallocene compounds for olefin polymerization MLX, AP1M1, AP2M1 PNMT 2397/4885NPC1 1938/4885RAB9A 3192/4885
US-20070135595-A1 Halogen substituted metallocene compounds for olefin polymerization AP2M1, AP1M1, CPNE4 PNMT 2352/4885NPC1 2210/4885RAB9A 3011/4885
US-20240188424-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, L1CAM, EPCAM PNMT 214/4885NPC1 3496/4885RAB9A 2008/4885
US-20240130230-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME L1CAM, TERT, ELAVL1 PNMT 88/4885NPC1 4145/4885RAB9A 2061/4885
US-20060160967-A1 Halogen substituted metallocene compounds for olefin polymerization OR10J3, ZRANB2, SLC39A3 PNMT 486/4885NPC1 2361/4885RAB9A 3543/4885
US-20060160968-A1 Process for producing substituted metallocene compounds for olefin polymerization OSBP, OSBPL3, OSBP2 PNMT 465/4885NPC1 950/4885RAB9A 3913/4885
US-20240114778-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, ELAVL1, EML4 PNMT 299/4885NPC1 3177/4885RAB9A 1112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.