SCHEMBL819755

SCHEMBL819755

C=C(C#N)C(=O)OC(CC)CCCCC

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
ALDH1A1 P00352 3/20 0.46
PRKCA P17252 1/20 0.38
PRKCD Q05655 1/20 0.38
CTSK P43235 1/20 0.34
MAPK1 P28482 2/20 0.33
MAPT P10636 2/20 0.33
ZDHHC7 Q9NXF8 1/20 0.33
GPR84 Q9NQS5 3/20 0.33
CA1 P00915 2/20 0.33
FFAR1 O14842 1/20 0.33
LMNA P02545 1/20 0.32
FAAH O00519 2/20 0.32
LCK P06239 1/20 0.32
PPARD Q03181 1/20 0.32
ZDHHC20 Q5W0Z9 1/20 0.32
ZDHHC2 Q9UIJ5 1/20 0.32
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15520525 0.95 TSHR (0.47) TSHRALDH1A1PRKCAPRKCDCTSK
SCHEMBL16174643 0.91 TSHR (0.46) TSHRALDH1A1MAPK1MAPTZDHHC7
SCHEMBL15519639 0.89 ALDH1A1 (0.50) TSHRALDH1A1PRKCAPRKCDCTSK
SCHEMBL26675834 0.87 TSHR (0.42) TSHRALDH1A1MAPK1MAPTGPR84
SCHEMBL3183024 0.86 TSHR (0.47) TSHRALDH1A1PRKCAPRKCDCTSK
SCHEMBL5889388 0.85 ALDH1A1 (0.57) TSHRALDH1A1CTSK
SCHEMBL1987524 0.83 TSHR (0.50) TSHRALDH1A1PRKCAPRKCDMAPK1
SCHEMBL15519572 0.83 TSHR (0.47) TSHRALDH1A1MAPTCA1LMNA
SCHEMBL3141579 0.83 TSHR (0.47) TSHRALDH1A1MAPTZDHHC7GPR84
SCHEMBL15519449 0.82 ALDH1A1 (0.53) TSHRALDH1A1PRKCAPRKCDCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026104704-A1 A COMBINATION, MEDICAL KIT AND MEDICAL DEVICE FOR TREATING AND/OR PREVENTING TISSUE LEAKAGE FUNDACIÓ INSTITUT DE INVESTIGACIÓ EN CIÈNCIES DE LA SALUT GERMANS TRIAS I PUJOL (ES) 2026-05-21 WO claimed
EP-4744687-A1 A COMBINATION, MEDICAL KIT AND MEDICAL DEVICE FOR TREATING AND/OR PREVENTING TISSUE LEAKAGE Aesculap AG (DE) 2026-05-20 EP claimed
US-20230138395-A1 PHARMACEUTICAL COMPOSITIONS OF A THERAPEUTIC POLYENE MACROLIDE AND METHODS OF THEIR USE BIOSERGEN AS (NO) 2023-05-04 US claimed
EP-4110305-A1 PHARMACEUTICAL COMPOSITIONS OF A THERAPEUTIC POLYENE MACROLIDE AND METHODS OF THEIR USE Biosergen AS (NO) 2023-01-04 EP claimed
EP-2747791-A1 PROTECTIVE WOUND DRESSING DEVICE FOR ORAL AND PHARYNGEAL SPACE Ethicon, Inc. (US) 2014-07-02 EP claimed
WO-2013028672-A1 PROTECTIVE WOUND DRESSING DEVICE FOR ORAL AND PHARYNGEAL SPACE ETHICON, INC. (US) 2013-02-28 WO claimed
JP-61040385-A None JP disclosed
WO-2026104704-A1 A COMBINATION, MEDICAL KIT AND MEDICAL DEVICE FOR TREATING AND/OR PREVENTING TISSUE LEAKAGE FUNDACIÓ INSTITUT DE INVESTIGACIÓ EN CIÈNCIES DE LA SALUT GERMANS TRIAS I PUJOL (ES) 2026-05-21 WO disclosed
EP-4744687-A1 A COMBINATION, MEDICAL KIT AND MEDICAL DEVICE FOR TREATING AND/OR PREVENTING TISSUE LEAKAGE Aesculap AG (DE) 2026-05-20 EP disclosed
EP-4717744-A1 USE OF A COMPOSITION BASED ON CYANOACRYLATE AND (METH)ACRYLATE Bostik SA (FR) 2026-04-01 EP disclosed
US-20250339579-A1 SURGICAL THREAD, SURGICAL SUTURE AND SURGICAL KIT B BRAUN SURGICAL SA (ES) 2025-11-06 US disclosed
US-20250339580-A1 MEDICAL TISSUE ADHESIVE COMPOSITION OKAPI MEDICAL LLC (US) 2025-11-06 US disclosed
EP-4587530-A1 CYANOACRYLATE COMPOSITIONS Henkel AG & Co. KGaA (DE) 2025-07-23 EP disclosed
US-20060088493-A1 Composition and process for the cosmetic treatment of keratin materials based on electrophilic monomers and non-silicone polymers L'OREAL S.A. (FR) 2006-04-27 US disclosed
US-20060085924-A1 Coloring composition comprising at least one pigment and at least one electrophilic cyanoacrylate monomer L'OREAL S.A. (FR) 2006-04-27 US disclosed
US-20060085922-A1 Oxidizing composition comprising at least one electrophilic monomer and at least one non-benzoquinone oxidant L'OREAL S.A. (FR) 2006-04-27 US disclosed
US-20060083706-A1 Haircare composition comprising at least one electrophilic monomer and micro- or nanoparticles of at least one solid lubricant L'OREAL S.A. (FR) 2006-04-20 US disclosed
US-20060083762-A1 Uses of compositions comprising electrophilic monomers and micro-particles or nanoparticles L'OREAL S.A. (FR) 2006-04-20 US disclosed
US-20060078523-A1 Composition comprising at least one electrophilic monomer and at least one acid in a cosmetically acceptable anhydrous medium, and use thereof for cosmetic treatment of the hair L'OREAL S.A. (FR) 2006-04-13 US disclosed
JP-S6140385-A COMPOSITION FOR ACRYLIC RESIN TOAGOSEI CHEM IND CO LTD 1986-02-26 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060088493-A1 Composition and process for the cosmetic treatment of keratin materials based on electrophilic monomers and non-silicone polymers KRT18, CUTA, MARK1 TSHR 4581/4885ALDH1A1 3552/4885PRKCA 184/4885
US-20060083762-A1 Uses of compositions comprising electrophilic monomers and micro-particles or nanoparticles KRT18, PRKDC, ACP1 TSHR 4297/4885ALDH1A1 828/4885PRKCA 61/4885
US-20060085922-A1 Oxidizing composition comprising at least one electrophilic monomer and at least one non-benzoquinone oxidant KRT18, GPX4, NOX4 TSHR 4243/4885ALDH1A1 303/4885PRKCA 368/4885
US-20060083706-A1 Haircare composition comprising at least one electrophilic monomer and micro- or nanoparticles of at least one solid lubricant MITF, CUTA, NACA TSHR 3327/4885ALDH1A1 43/4885PRKCA 2363/4885
US-20230138395-A1 PHARMACEUTICAL COMPOSITIONS OF A THERAPEUTIC POLYENE MACROLIDE AND METHODS OF THEIR USE CEL, LIPA, HDAC6 TSHR 4097/4885ALDH1A1 4396/4885PRKCA 1639/4885
US-20060085924-A1 Coloring composition comprising at least one pigment and at least one electrophilic cyanoacrylate monomer CBR1, MMAB, ALDH1A2 TSHR 4776/4885ALDH1A1 21/4885PRKCA 1826/4885
US-20060078523-A1 Composition comprising at least one electrophilic monomer and at least one acid in a cosmetically acceptable anhydrous medium, and use thereof for cosmetic treatment of the hair HOGA1, OAT, SUCLG1 TSHR 4459/4885ALDH1A1 18/4885PRKCA 3118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.