Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29672565 | 0.98 | CYP1A2 (0.36) | CYP1A2CYP2A6ALDH1A1MEN1KMT2A | |
| Iodide SCHEMBL28719254 | 0.98 | KDM4E (0.38) | CYP1A2CYP2A6ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL820541 | 0.98 | CYP1A2 (0.36) | CYP1A2CYP2A6ALDH1A1MEN1KMT2A | |
| SCHEMBL22427651 | 0.88 | MAPT (0.36) | CYP2A6ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL20006913 | 0.88 | SMN1; SMN2 (0.41) | ALDH1A1MEN1KMT2AACHETSHR | |
| SCHEMBL16545308 | 0.82 | TSHR (0.44) | CYP1A2ALDH1A1TSHRCA1CA2 | |
| SCHEMBL20434169 | 0.82 | MEN1 (0.30) | ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL925633 | 0.78 | HTR2A (0.32) | — | |
| SCHEMBL8336707 | 0.75 | EPHB4 (0.33) | KMT2AKDM4ETDP1L3MBTL1 | |
| SCHEMBL1156328 | 0.73 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AACHETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114644661-A | Imidazole carbene iron complex and application thereof | 北京服装学院 | 2022-06-21 | — | — | CN | disclosed |
| US-20190352262-A1 | New Pleuromutilin Antibiotic Compounds, Compositions and Methods of Use and Synthesis | UNIV YALE (US) | 2019-11-21 | — | — | US | disclosed |
| EP-2339594-B1 | COMPOSITION FOR PRODUCING METAL FILM, METHOD FOR PRODUCING METAL FILM, AND METHOD FOR PRODUCING METAL POWDER | TOSOH CORP (JP) | 2018-01-03 | — | — | EP | disclosed |
| US-9624581-B2 | Composition for production of metal film, method for producing metal film and method for producing metal powder | TOSOH CORPORATION (JP) | 2017-04-18 | — | — | US | disclosed |
| EP-2513029-B1 | CARBOXYLATION OF TERMINAL ALKYNES | AGENCY SCIENCE TECH & RES (SG) | 2017-04-05 | — | — | EP | disclosed |
| EP-1534722-B1 | RHODIUM AND IRIDIUM COMPLEXES | MERCK PATENT GMBH (DE) | 2017-03-22 | — | — | EP | disclosed |
| US-20140275329-A1 | Ruthenium Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts | DOW SILICONES CORPORATION | 2014-09-18 | — | — | US | disclosed |
| US-20140275329-A1 | Ruthenium Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts | DOW SILICONES CORPORATION | 2014-09-18 | — | — | US | disclosed |
| US-8816127-B2 | Carboxylation of terminal alkynes | AGENCY FOR SCIENCE TECHNOLOGY AND RESEARCH (SG) | 2014-08-26 | — | — | US | disclosed |
| EP-2289902-B1 | Rhodium and iridium complexes | MERCK PATENT GMBH (DE) | 2014-04-30 | — | — | EP | disclosed |
| US-20100160683-A1 | Process for Production of 2-(Substituted Phenyl)-3,3,3-Trifluoropropene Compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-06-24 | — | — | US | disclosed |
| US-7534853-B2 | Rhodium and iridium complexes | MERCK PATENT GMBH (DE) | 2009-05-19 | — | — | US | disclosed |
| US-7094897-B2 | Rhodium and iridium complexes | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2006-08-22 | — | — | US | disclosed |
| US-20060127696-A1 | Rhodium and iridium complexes | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2006-06-15 | — | — | US | disclosed |
| US-20060065890-A1 | Rhodium and iridium complexes | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2006-03-30 | — | — | US | disclosed |
| EP-1379534-B1 | RHODIUM AND IRIDIUM COMPLEXES | COVION ORGANIC SEMICONDUCTORS (DE) | 2004-12-15 | — | — | EP | disclosed |
| US-6815562-B2 | REACTION OF NITROHALOGENS WITH ANILINES, A BASE AND A CATALYST, HYDROGENATION, | BAYER AKTIENGESELLSCHAFT (DE) | 2004-11-09 | — | — | US | disclosed |
| US-20040143138-A1 | Process for the preparation of nitrodiphenylamines | LANXESS DEUTSCHLAND GMBH (DE) | 2004-07-22 | — | — | US | disclosed |
| EP-1437341-A1 | Process for the preparation of nitrodiphenylamines | Bayer Aktiengesellschaft (DE) | 2004-07-14 | — | — | EP | disclosed |
| US-20040133004-A1 | Rhodium and iridium complexes | MERCK PATENT GMBH (DE) | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190352262-A1 | New Pleuromutilin Antibiotic Compounds, Compositions and Methods of Use and Synthesis | PLEC, MLN, MRPL21 | CYP1A2 2972/4885CYP2A6 1891/4885ALDH1A1 3977/4885 |
| US-20040143138-A1 | Process for the preparation of nitrodiphenylamines | HNMT, PNMT, NNMT | CYP1A2 28/4885CYP2A6 352/4885ALDH1A1 998/4885 |
| US-20060065890-A1 | Rhodium and iridium complexes | RPIA, INPP5B, SIRT5 | CYP1A2 1432/4885CYP2A6 2619/4885ALDH1A1 1107/4885 |
| US-20100160683-A1 | Process for Production of 2-(Substituted Phenyl)-3,3,3-Trifluoropropene Compound | PEX3, SCO2, LPO | CYP1A2 1489/4885CYP2A6 2322/4885ALDH1A1 3618/4885 |
| US-20040133004-A1 | Rhodium and iridium complexes | RPIA, SIRT5, INPP5B | CYP1A2 1543/4885CYP2A6 2729/4885ALDH1A1 1115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.