Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | GNPAT | O15228 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 2/20 | 0.33 |
| ▸ | FNTB | P49356 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | BMP1 | P13497 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8368760 | 1.00 | SLC22A6 (0.38) | SLC22A6TDP1CA2CA4GNPAT | |
| SCHEMBL16656708 | 1.00 | SLC22A6 (0.38) | SLC22A6TDP1CA2CA4GNPAT | |
| SCHEMBL27267642 | 0.85 | GNPAT (0.44) | CA2CA4GNPATSMN1; SMN2FNTA | |
| SCHEMBL13377669 | 0.83 | GNPAT (0.46) | CA2CA4GNPATENPEPBMP1 | |
| SCHEMBL27267745 | 0.83 | GNPAT (0.46) | CA2CA4GNPATENPEPBMP1 | |
| SCHEMBL14490960 | 0.83 | SLC22A6 (0.36) | SLC22A6TDP1CA2CA4GNPAT | |
| SCHEMBL16348723 | 0.83 | SLC22A6 (0.36) | SLC22A6TDP1CA2CA4GNPAT | |
| SCHEMBL8729434 | 0.83 | SLC22A6 (0.36) | SLC22A6TDP1CA2CA4GNPAT | |
| N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL2220 | 0.82 | CA2 (0.45) | SLC22A6TDP1CA2CA4GNPAT | |
| SCHEMBL13474987 | 0.82 | ALDH1A1 (0.43) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238459-A1 | Granzyme-Activatable Membrane-Interacting Peptides and Methods of Use | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2024-07-18 | — | — | US | disclosed |
| US-20230346951-A1 | MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS | YALE UNIVERSITY | 2023-11-02 | — | — | US | disclosed |
| US-11712483-B2 | Activatable membrane-interacting peptides and methods of use | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-08-01 | — | — | US | disclosed |
| US-20230190616-A1 | COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2023-06-22 | — | — | US | disclosed |
| US-20230114807-A1 | RADIOLABELED COMPOUNDS TARGETING THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN | PROVINCIAL HEALTH SERVICES AUTHORITY (CA) | 2023-04-13 | — | — | US | disclosed |
| US-20220002342-A1 | DECARBOXYLATIVE CONJUGATE ADDITIONS AND APPLICATIONS THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY | 2022-01-06 | — | — | US | disclosed |
| US-11136349-B2 | Decarboxylative conjugate additions and applications thereof | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2021-10-05 | — | — | US | disclosed |
| US-20170304383-A1 | SMALL MOLECULE RAS INHIBITORS | OHIO STATE INNOVATION FOUNDATION | 2017-10-26 | — | — | US | disclosed |
| US-9789209-B2 | Activatable membrane-interacting peptides and methods of use | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, BERKE (US) | 2017-10-17 | — | — | US | disclosed |
| US-9771392-B2 | Compounds which inhibit neuronal exocytosis | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2017-09-26 | — | — | US | disclosed |
| US-20110081309-A1 | COMPOSITIONS COMPRISING A SUPERHYDROPHILIC AMPHIPHILIC COPOLYMER AND A MICELLAR THICKENER | KENVUE BRANDS LLC | 2011-04-07 | — | — | US | disclosed |
| US-20110081310-A1 | COMPOSITIONS COMPRISING SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS AND METHODS OF USE THEREOF | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. | 2011-04-07 | — | — | US | disclosed |
| US-20110082290-A1 | SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS AND PROCESSES FOR MAKING THE SAME | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2011-04-07 | — | — | US | disclosed |
| US-7867592-B2 | Methods, compositions and devices, including electroosmotic pumps, comprising coated porous surfaces | EKSIGENT TECHNOLOGIES, INC. (US) | 2011-01-11 | — | — | US | disclosed |
| US-20100196502-A1 | Isoform Selective HDAC Inhibitors | GEORGETOWN UNIVERSITY (US) | 2010-08-05 | — | — | US | disclosed |
| US-20090176679-A1 | Detergent Compositions | Henkel IP & Holding GmbH (DE) | 2009-07-09 | — | — | US | disclosed |
| US-7511039-B2 | β-sheet mimetics and use thereof as inhibitors of biologically active peptides or proteins | MYRIAD GENETICS, INC. (US) | 2009-03-31 | — | — | US | disclosed |
| US-20080179188-A1 | METHODS, COMPOSITIONS AND DEVICES, INCLUDING ELECTROOSMOTIC PUMPS, COMPRISING COATED POROUS SURFACES | EKSIGENT TECHNOLOGIES, INC. (US) | 2008-07-31 | — | — | US | disclosed |
| US-7316811-B2 | Multi-arm polypeptide-poly (ethylene glycol) block copolymers as drug delivery vehicles | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2008-01-08 | — | — | US | disclosed |
| US-20060276408-A1 | Beta-sheet mimetics and use thereof as inhibitors of biologically active peptides or proteins | MYRIAD GENETICS, INCORPORATED (US) | 2006-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11712483-B2 | Activatable membrane-interacting peptides and methods of use | ANXA5, PLA2G2A, F13B | SLC22A6 3124/4885TDP1 2290/4885CA2 1711/4885 |
| US-20240238459-A1 | Granzyme-Activatable Membrane-Interacting Peptides and Methods of Use | GZMB, PRF1, PLA2G2A | SLC22A6 2901/4885TDP1 1679/4885CA2 1486/4885 |
| US-20230190616-A1 | COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES | GLA, ALG3, ANXA6 | SLC22A6 2182/4885TDP1 2853/4885CA2 1237/4885 |
| US-20220002342-A1 | DECARBOXYLATIVE CONJUGATE ADDITIONS AND APPLICATIONS THEREOF | PTMS, DNPEP, QPCT | SLC22A6 1556/4885TDP1 3297/4885CA2 2519/4885 |
| US-20110081310-A1 | COMPOSITIONS COMPRISING SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS AND METHODS OF USE THEREOF | ABHD16A, LIPA, ABHD12 | SLC22A6 857/4885TDP1 1325/4885CA2 2938/4885 |
| US-20110081309-A1 | COMPOSITIONS COMPRISING A SUPERHYDROPHILIC AMPHIPHILIC COPOLYMER AND A MICELLAR THICKENER | ABHD16A, DSG1, CUTA | SLC22A6 2595/4885TDP1 722/4885CA2 3914/4885 |
| US-20230346951-A1 | MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS | ASGR1, MSR1, LDLR | SLC22A6 2503/4885TDP1 3279/4885CA2 4350/4885 |
| US-20170304383-A1 | SMALL MOLECULE RAS INHIBITORS | KRAS, NRAS, HRAS | SLC22A6 3598/4885TDP1 3878/4885CA2 3616/4885 |
| US-20230114807-A1 | RADIOLABELED COMPOUNDS TARGETING THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN | FOLH1, KLK3, PSMA3 | SLC22A6 403/4885TDP1 4781/4885CA2 275/4885 |
| US-20060276408-A1 | Beta-sheet mimetics and use thereof as inhibitors of biologically active peptides or proteins | SERPINB1, SERPINE1, SERPINA2 | SLC22A6 4742/4885TDP1 905/4885CA2 3894/4885 |
| US-11136349-B2 | Decarboxylative conjugate additions and applications thereof | PTMS, DNPEP, QPCT | SLC22A6 1556/4885TDP1 3297/4885CA2 2519/4885 |
| US-20100196502-A1 | Isoform Selective HDAC Inhibitors | HDAC5, HDAC6, HDAC3 | SLC22A6 3502/4885TDP1 1198/4885CA2 1148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.