SCHEMBL823206

SCHEMBL823206

O=C(O)c1ccc2c3c(ccc(C(=O)NCCc4ccc(F)cc4)c13)C(=O)N(c1ccccc1)C2=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.48
KDM4E B2RXH2 2/20 0.47
ALDH1A1 P00352 2/20 0.47
POLB P06746 1/20 0.47
APOBEC3A P31941 1/20 0.47
RECQL P46063 1/20 0.47
CASP6 P55212 1/20 0.47
APOBEC3G Q9HC16 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
NPC1 O15118 4/20 0.47
RAB9A P51151 4/20 0.47
LMNA P02545 1/20 0.45
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44
KMT2A Q03164 1/20 0.44
CNR1 P21554 1/20 0.43
CNR2 P34972 1/20 0.43
PPARA Q07869 1/20 0.43
SLC6A5 Q9Y345 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL823143 0.92 KDM4E (0.52) MAPTKDM4EALDH1A1POLBAPOBEC3A
SCHEMBL822568 0.86 MAPT (0.44) MAPTKDM4EALDH1A1POLBAPOBEC3A
SCHEMBL823207 0.83 THRB (0.49) MAPTKDM4EALDH1A1POLBAPOBEC3A
SCHEMBL12104600 0.79 THRB (0.47) MAPTKDM4EALDH1A1POLBAPOBEC3A
SCHEMBL822751 0.78 CNR2 (0.42) MAPTKDM4EALDH1A1POLBAPOBEC3A
SCHEMBL822668 0.76 RAB9A (0.62) MAPTALDH1A1L3MBTL1NPC1RAB9A
SCHEMBL16352053 0.76 RAB9A (0.62) MAPTALDH1A1L3MBTL1NPC1RAB9A
SCHEMBL3796253 0.76 RAB9A (0.62) MAPTALDH1A1L3MBTL1NPC1RAB9A
SCHEMBL12104731 0.75 NPC1 (0.47) MAPTKDM4EALDH1A1NPC1RAB9A
SCHEMBL823145 0.75 KMT2A (0.47) MAPTKDM4EALDH1A1POLBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530270-B2 Methods of preparing semiconductive compositions and devices EASTMAN KODAK COMPANY (US) 2013-09-10 US disclosed
US-8411489-B2 Semiconducting devices and methods of preparing EASTMAN KODAK COMPANY (US) 2013-04-02 US disclosed
US-8314265-B2 Aromatic amic acids or amic esters and compositions EASTMAN KODAK COMPANY (US) 2012-11-20 US disclosed
WO-2011137139-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS EASTMAN KODAK COMPANY (US) 2011-11-03 WO disclosed
WO-2011137133-A2 SEMICONDUCTING DEVICES AND METHODS OF PREPARING EASTMAN KODAK COMPANY (US) 2011-11-03 WO disclosed
WO-2011137137-A1 SEMICONDUCTING ARTICLES EASTMAN KODAK COMPANY (US) 2011-11-03 WO disclosed
US-20110269967-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS BANK OF AMERICA, N.A., AS AGENT 2011-11-03 US disclosed
US-20110269966-A1 SEMICONDUCTING ARTICLES CITICORP NORTH AMERICA, INC., AS AGENT 2011-11-03 US disclosed
US-20110269265-A1 METHODS OF PREPARING SEMICONDUCTIVE COMPOSITIONS AND DEVICES KODAK REALTY INC. 2011-11-03 US disclosed
US-20110266523-A1 SEMICONDUCTING DEVICES AND METHODS OF PREPARING BANK OF AMERICA, N.A., AS AGENT 2011-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110269966-A1 SEMICONDUCTING ARTICLES ALAD, PORCN, DDC MAPT 1981/4885KDM4E 1041/4885ALDH1A1 508/4885
US-20110269967-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS DDC, AADAC, MYOC MAPT 1597/4885KDM4E 664/4885ALDH1A1 745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.