SCHEMBL827155

SCHEMBL827155

CC(C)c1c[nH]cc1C(C)C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 6/20 0.35
GABRB1 P18505 4/20 0.35
GABRB2 P47870 3/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
GABRG2 P18507 2/20 0.35
GABRB3 P28472 2/20 0.35
FAAH O00519 1/20 0.35
LMNA P02545 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
PTGS1 P23219 1/20 0.35
SLC6A2 P23975 1/20 0.35
HTR2C P28335 1/20 0.35
GABRA5 P31644 1/20 0.35
GABRA3 P34903 1/20 0.35
HTR2B P41595 1/20 0.35
GABRA2 P47869 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24499214 0.86
SCHEMBL12122255 0.82
SCHEMBL20133058 0.80
SCHEMBL22644586 0.76
SCHEMBL18650007 0.76 FABP3 (0.30) FABP3FABP4
SCHEMBL20133057 0.74 KDM5A (0.40)
SCHEMBL1126813 0.74 NOTUM (0.52) CYP1A2HPGDTSHRFABP3FABP4
SCHEMBL2990926 0.73 HCAR2 (0.31)
SCHEMBL16921537 0.72 GABRA1 (0.37) GABRA1GABRB1GABRB2CA1CA2
SCHEMBL1156156 0.69 NR4A2 (0.40) CA1CA2LMNATSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8362278-B2 Methods for the conversion of a substituted furan to a substituted pyrrole CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2013-01-29 US claimed
US-20120083609-A1 METHODS FOR THE CONVERSION OF A SUBSTITUTED FURAN TO A SUBSTITUTED PYRROLE CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-04-05 US claimed
CN-122070352-A Sustainable aviation fuel produced from normal alpha olefin byproducts and method thereof 切弗朗菲利浦化学公司 2026-05-19 CN disclosed
US-12618016-B2 Methods for producing aviation fuels CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2026-05-05 US disclosed
US-20260103649-A1 SUSTAINABLE AVIATION FUEL FROM NORMAL ALPHA OLEFIN BYPRODUCTS AND PROCESS FOR SAME CHEVRON PHILLIPS CHEMICAL CO LP (US) 2026-04-16 US disclosed
WO-2026043730-A1 METHODS FOR PRODUCING AVIATION FUELS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2026-02-26 WO disclosed
US-20260049256-A1 METHODS FOR PRODUCING AVIATION FUELS CHEVRON PHILLIPS CHEMICAL COMPANY LP 2026-02-19 US disclosed
US-12540287-B2 Sustainable aviation fuel from normal alpha olefin byproducts and process for same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2026-02-03 US disclosed
US-12528999-B2 Sustainable jet fuel and process CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2026-01-20 US disclosed
WO-2025054252-A1 SUSTAINABLE JET FUEL AND PROCESS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2025-03-13 WO disclosed
US-20250084331-A1 SUSTAINABLE AVIATION FUEL FROM NORMAL ALPHA OLEFIN BYPRODUCTS AND PROCESS FOR SAME CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2025-03-13 US disclosed
US-7612218-B2 Process for production of heteroaryl-type boron compounds with iridium catalyst MITSUBISHI RAYON CO., LTD. (JP) 2009-11-03 US disclosed
US-7572784-B2 Compounds and methods for inhibiting mitotic progression MILLENNIUM PHARMACEUTICALS, INC. (US) 2009-08-11 US disclosed
EP-1771450-B9 COMPOUNDS AND METHODS FOR INHIBITING MITOTIC PROGRESSION BY INHIBITION OF AURORA KINASE MILLENNIUM PHARM INC (US) 2008-12-24 EP disclosed
EP-1905773-A2 Compounds and methods for inhibiting mitotic progression by inhibition of aurora kinase MILLENNIUM PHARMACEUTICALS, INC. (US) 2008-04-02 EP disclosed
US-20080045501-A1 Pyridobenzazepine compounds and methods for inhibiting mitotic progression MILLENNIUM PHARMACEUTICALS, INC. (US) 2008-02-21 US disclosed
EP-1771450-B1 COMPOUNDS AND METHODS FOR INHIBITING MITOTIC PROGRESSION BY INHIBITION OF AURORA KINASE MILLENNIUM PHARM INC (US) 2007-12-19 EP disclosed
US-20070185087-A1 Compounds and methods for inhibiting mitotic progression MILLENNIUM PHARMACEUTICALS, INC. (US) 2007-08-09 US disclosed
US-20050148775-A1 Process for production of heteroaryl-type boron compounds with iridium catalyst MITSUBISHI RAYON CO., LTD. (JP) 2005-07-07 US disclosed
EP-1481978-A1 PROCESS FOR PRODUCTION OF HETEROARYL-TYPE BORON COMPOUNDS WITH IRIDIUM CATALYST Mitsubishi Rayon Co., Ltd. (JP) 2004-12-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12618016-B2 Methods for producing aviation fuels CYP4F8, CYP8B1, CYP2E1 GABRA1 3274/4885GABRB1 2416/4885GABRB2 2625/4885
US-20120083609-A1 METHODS FOR THE CONVERSION OF A SUBSTITUTED FURAN TO A SUBSTITUTED PYRROLE PAH, CPS1, ASNS GABRA1 3232/4885GABRB1 3015/4885GABRB2 2608/4885
US-20250084331-A1 SUSTAINABLE AVIATION FUEL FROM NORMAL ALPHA OLEFIN BYPRODUCTS AND PROCESS FOR SAME ECH1, YAP1, ECHS1 GABRA1 3236/4885GABRB1 3402/4885GABRB2 3388/4885
US-20260103649-A1 SUSTAINABLE AVIATION FUEL FROM NORMAL ALPHA OLEFIN BYPRODUCTS AND PROCESS FOR SAME YAP1, CYP4F8, SCD GABRA1 968/4885GABRB1 1045/4885GABRB2 1064/4885
US-20070185087-A1 Compounds and methods for inhibiting mitotic progression AURKC, AURKA, AURKB GABRA1 4822/4885GABRB1 4811/4885GABRB2 4817/4885
US-20050148775-A1 Process for production of heteroaryl-type boron compounds with iridium catalyst PIN4, IPO5, HLCS GABRA1 691/4885GABRB1 792/4885GABRB2 985/4885
US-12528999-B2 Sustainable jet fuel and process CYP2E1, ADH1C, PCCA GABRA1 841/4885GABRB1 789/4885GABRB2 743/4885
US-20260049256-A1 METHODS FOR PRODUCING AVIATION FUELS CYP4F8, CPT1A, CBR1 GABRA1 3112/4885GABRB1 2556/4885GABRB2 2845/4885
US-12540287-B2 Sustainable aviation fuel from normal alpha olefin byproducts and process for same ADH1A, ADH1C, YAP1 GABRA1 1162/4885GABRB1 1020/4885GABRB2 1127/4885
US-20080045501-A1 Pyridobenzazepine compounds and methods for inhibiting mitotic progression AURKB, AURKC, AURKA GABRA1 4405/4885GABRB1 3978/4885GABRB2 3946/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.