Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8303601 | 0.76 | HRH3 (0.44) | ITGB3ITGA2B | |
| SCHEMBL8617194 | 0.76 | CCR2 (0.32) | KDM4E | |
| SCHEMBL8306140 | 0.71 | KDM4E (0.39) | KDM4EITGB3ITGA2B | |
| SCHEMBL8304068 | 0.67 | CYP2D6 (0.39) | ITGB3ITGA2B | |
| SCHEMBL8305336 | 0.65 | KDM4E (0.43) | KDM4EITGB3ITGA2B | |
| SCHEMBL8300039 | 0.63 | ITGB3 (0.40) | HSD11B1ITGB3ITGA2B | |
| SCHEMBL8304874 | 0.62 | FFAR4 (0.41) | — | |
| SCHEMBL8301158 | 0.62 | CCR2 (0.35) | — | |
| SCHEMBL8300260 | 0.62 | ITGB3 (0.38) | ITGB3ITGA2B | |
| SCHEMBL20322919 | 0.61 | ALOX15 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808306-B1 | NEW DERIVATIVES OF PYRIDINE OR PYRIDAZINE, PROCESS FOR PRODUCTION THEREOF AND MEDICAMENTS CONTAINING THESE COMPOUNDS | ROCHE DIAGNOSTICS GMBH (DE) | 1999-08-04 | — | — | EP | disclosed |