Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | F13A1 | P00488 | 1/20 | 0.34 |
| ▸ | TGM1 | P22735 | 1/20 | 0.34 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Vinyl Ether SCHEMBL1412752 | 0.93 | MAPT (0.37) | CYP2A6MAPTCA1CA2CA9 | |
| SCHEMBL473606 | 0.86 | CHRNB2 (0.34) | MAPTCA1CA2CA9LMNA | |
| SCHEMBL14289128 | 0.78 | ALDH1A1 (0.44) | MAPTTGM2LMNAMAPK1MEN1 | |
| SCHEMBL11965976 | 0.78 | ESR2 (0.33) | MAPTLMNAMAPK1RAB9AALDH1A1 | |
| SCHEMBL1412755 | 0.77 | MAPT (0.32) | CYP2A6MAPTCA1CA2CA9 | |
| SCHEMBL3791265 | 0.75 | CYP2A6 (0.38) | CYP2A6MAPTCA1CA2CA9 | |
| SCHEMBL3791263 | 0.75 | CYP2A6 (0.38) | CYP2A6MAPTCA1CA2CA9 | |
| SCHEMBL24636596 | 0.74 | CHRNB2 (0.30) | — | |
| SCHEMBL126186 | 0.74 | ALDH1A1 (0.58) | CYP2A6LMNAALDH1A1 | |
| SCHEMBL17186614 | 0.74 | NPC1 (0.32) | MAPTLMNAMAPK1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240349587-A1 | In-Situ crosslinking of 9,9' -spirobifluorene-based compounds for use in optoelectronic and/or in photoelectrochemical devices and manufacture thereof | KAUNAS UNIVERSITY OF TECHNOLOGY (LT) | 2024-10-17 | — | — | US | disclosed |
| EP-4447643-A1 | IN-SITU CROSSLINKING OF 9,9`-SPIROBIFLUORENE-BASED COMPOUNDS FOR USE IN OPTOELECTRONIC AND/OR PHOTOELECTROCHEMICAL DEVICES AND MANUFACTURE THEREOF | Kaunas University of Technology (LT) | 2024-10-16 | — | — | EP | disclosed |
| CN-113666883-B | Method for synthesizing 4-vinyl isoxazole derivative | 华南理工大学 | 2023-06-16 | — | — | CN | disclosed |
| EP-3555055-B1 | HYDROXY ISOXAZOLE COMPOUNDS USEFUL AS GPR120 AGONISTS | MERCK SHARP & DOHME LLC (US) | 2022-08-03 | — | — | EP | disclosed |
| CN-113666883-A | Method for synthesizing 4-vinyl isoxazole derivative | 华南理工大学 | 2021-11-19 | — | — | CN | disclosed |
| US-10864211-B2 | Hydroxy isoxazole compounds useful as GPR120 agonists | MERCK SHARP & DOHME CORP. (US) | 2020-12-15 | — | — | US | disclosed |
| EP-3555055-A1 | HYDROXY ISOXAZOLE COMPOUNDS USEFUL AS GPR120 AGONISTS | Merck Sharp & Dohme Corp. (US) | 2019-10-23 | — | — | EP | disclosed |
| US-20190269679-A1 | HYDROXY ISOXAZOLE COMPOUNDS USEFUL AS GPR120 AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2019-09-05 | — | — | US | disclosed |
| WO-2018111734-A1 | HYDROXY ISOXAZOLE COMPOUNDS USEFUL AS GPR120 AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2018-06-21 | — | — | WO | disclosed |
| US-9617256-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2017-04-11 | — | — | US | disclosed |
| US-20020197551-A1 | Toner, and process for producing toner | TAZAWA YAYOI (JP) | 2002-12-26 | — | — | US | disclosed |
| CN-1384401-A | Compensating developer and developing method | CANON KK (JP) | 2002-12-11 | — | — | CN | disclosed |
| EP-1237051-A2 | Replenishing developer and developing method | CANON KABUSHIKI KAISHA (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-6372400-B1 | FOR DEVELOPING AN ELECTROSTATIC LATENT IMAGE BY ELECTROPHOTOGRAPHY | CANON KABUSHIKI KAISHA (JP) | 2002-04-16 | — | — | US | disclosed |
| US-6358658-B1 | COLOR TONERS AND BINDERS | CANON KABUSHIKI KAISHA (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-0801335-B1 | Magnetic coated carrier, two-component type developer and developing method | CANON KK (JP) | 2001-08-29 | — | — | EP | disclosed |
| EP-1065571-A2 | Carrier for use in electrophotography, two-component type developer and image forming method | CANON KABUSHIKI KAISHA (JP) | 2001-01-03 | — | — | EP | disclosed |
| US-6165663-A | Magnetic coated carrier two-component type developer and developing method | CANON KABUSHIKI KAISHA (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-1003080-A1 | Toner, and process for producing toner | CANON KABUSHIKI KAISHA (JP) | 2000-05-24 | — | — | EP | disclosed |
| EP-0801335-A1 | Magnetic coated carrier, two-component type developer and developing method | CANON KABUSHIKI KAISHA (JP) | 1997-10-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240349587-A1 | In-Situ crosslinking of 9,9' -spirobifluorene-based compounds for use in optoelectronic and/or in photoelectrochemical devices and manufacture thereof | INTS9, SLC6A9, SLC19A1 | CYP2A6 1243/4885MAPT 473/4885CA1 4264/4885 |
| US-10864211-B2 | Hydroxy isoxazole compounds useful as GPR120 agonists | GPR119, GPR88, GPR180 | CYP2A6 1558/4885MAPT 4490/4885CA1 4632/4885 |
| US-20190269679-A1 | HYDROXY ISOXAZOLE COMPOUNDS USEFUL AS GPR120 AGONISTS | GPR119, GPR88, GPR180 | CYP2A6 1558/4885MAPT 4490/4885CA1 4632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.