Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Butanal. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butanal SCHEMBL7550402 | 0.87 | — | — | |
| Butanal SCHEMBL7777055 | 0.84 | ALDH1A1 (0.67) | ALDH1A1TSHRADH1BADH1AADH7 | |
| Sulfurous Acid SCHEMBL7770699 | 0.84 | HIF1A (0.37) | ALDH1A1TSHRHIF1A | |
| Sulfurous Acid SCHEMBL8002563 | 0.84 | HIF1A (0.37) | ALDH1A1TSHRHIF1A | |
| Propionaldehyde SCHEMBL8424150 | 0.81 | — | — | |
| Glutaral SCHEMBL1359455 | 0.79 | HIF1A (0.56) | ALDH1A1TSHRFAAHTRPV1HIF1A | |
| Glutaral SCHEMBL456725 | 0.79 | HIF1A (0.56) | ALDH1A1TSHRFAAHTRPV1HIF1A | |
| Butanal SCHEMBL10448612 | 0.78 | — | — | |
| Butanal SCHEMBL27897686 | 0.78 | — | — | |
| Butanal SCHEMBL597713 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TSHRADH1BADH1AADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727712-B1 | Integral silver halide diffusion transfer lithographic printing plates | EASTMAN KODAK CO (US) | 1999-10-27 | — | — | EP | disclosed |
| US-5969065-A | POLYMER DISPERSION PREPARED BY EMULSION POLYMERIZATION OF VINYL COMPOUNDS COMPRISING EMPLOYING REDOX CATALYST COMPRISING OXIDIZING AGENT AND REDUCING AGENT COMPRISING BIFUNCTIONAL ALDEHYDE MASKED AS BISULFITE ADDUCT BOUND TO POLYMER | CLARIANT GMBH (DE) | 1999-10-19 | — | — | US | disclosed |
| EP-0565459-B1 | Novel photographic developing solution and use thereof in the high contrast development of nucleated photographic elements | EASTMAN KODAK CO (US) | 1998-09-16 | — | — | EP | disclosed |
| US-5744418-A | REDUCING AGENT COMPRISING BIFUNCTIONAL ALDEHYDE MASKED AS BISULFITE ADDUCT | CLARIANT GMBH (DE) | 1998-04-28 | — | — | US | disclosed |
| EP-0727712-A1 | Integral silver halide diffusion transfer lithographic printing plates | EASTMAN KODAK COMPANY (US) | 1996-08-21 | — | — | EP | disclosed |
| EP-0329086-B1 | Image forming method for silver halide light-sensitive materials | KONISHIROKU PHOTO IND (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5457011-A | Containing polyoxyalkylated phosphate ester to inhibit sludge formation | EASTMAN KODAK COMPANY (US) | 1995-10-10 | — | — | US | disclosed |
| US-5453348-A | Silver halide color photographic light-sensitive material | KONICA CORPORATION (JP) | 1995-09-26 | — | — | US | disclosed |
| US-5352568-A | Bleaching with solution containing ferric complex salt of organic acid, halide compound, buffer, fixing | KONICA CORPORATION (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0244177-B1 | Method for processing light-sensitive silver halide color photographic material | KONISHIROKU PHOTO IND (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-4778743-A | ALDEHYDE DERIVATIVE | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1988-10-18 | — | — | US | disclosed |
| EP-0270217-A2 | Bleach-fixing solution having good processing performance and method for processing light-sensitive material using the same | KONICA CORPORATION (JP) | 1988-06-08 | — | — | EP | disclosed |
| EP-0270382-A2 | Method for treating photographic processing waste solution | KONICA CORPORATION (JP) | 1988-06-08 | — | — | EP | disclosed |
| US-4705377-A | Automatic processing machine for light-sensitive color photographic material | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1987-11-10 | — | — | US | disclosed |
| EP-0244177-A2 | Method for processing light-sensitive silver halide color photographic material | KONICA CORPORATION (JP) | 1987-11-04 | — | — | EP | disclosed |
| US-4623613-A | CONTROLLING SULFITE CONCENTRATION TO PREVENT FORMATION OF SILVER SULFIDE | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1986-11-18 | — | — | US | disclosed |
| EP-0186158-A2 | Method of processing light-sensitive silver halide photographic material | KONICA CORPORATION (JP) | 1986-07-02 | — | — | EP | disclosed |
| EP-0165805-A2 | Automatic processing machine for light-sensitive color photographic material | KONICA CORPORATION (JP) | 1985-12-27 | — | — | EP | disclosed |
| US-4125402-A | Method of processing silver dye bleaching materials and preparations suitable for the dye and silver bleaching | CIBA-GEIGY AG (CH) | 1978-11-14 | — | — | US | disclosed |
| US-4033771-A | IRON OR COBALT COMPLEX WITH POLYCARBOXYLIC ACID, THIOSULFATES, CARBONYL BISULFITE ADDUCT | EASTMAN KODAK COMPANY (US) | 1977-07-05 | — | — | US | disclosed |