Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5937208 | 0.84 | ALDH1A1 (0.47) | APOBEC3AAPOBEC3GALDH1A1MAPTKMT2A | |
| SCHEMBL5727138 | 0.84 | ALDH1A1 (0.48) | APOBEC3AAPOBEC3GALDH1A1MAPTGABRA1 | |
| SCHEMBL14710629 | 0.81 | KMT2A (0.42) | APOBEC3AAPOBEC3GALDH1A1MAPTKMT2A | |
| SCHEMBL22697032 | 0.81 | MAPK1 (0.43) | APOBEC3AAPOBEC3GALDH1A1MAPTKMT2A | |
| SCHEMBL4355684 | 0.81 | LMNA (0.46) | APOBEC3AAPOBEC3GALDH1A1MAPTKMT2A | |
| SCHEMBL23769132 | 0.81 | ALDH1A1 (0.46) | APOBEC3AAPOBEC3GALDH1A1MAPTGABRA1 | |
| SCHEMBL1990691 | 0.81 | ALDH1A1 (0.46) | APOBEC3AAPOBEC3GALDH1A1MAPTGABRA1 | |
| SCHEMBL31553574 | 0.81 | ALDH1A1 (0.49) | ALDH1A1MAPTHPGDKDM4EHSD17B10 | |
| SCHEMBL11656354 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MAPTGABRA1GABRA5HPGD | |
| SCHEMBL29173554 | 0.79 | ALDH1A1 (0.44) | APOBEC3AAPOBEC3GALDH1A1MAPTGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12370192-B2 | Azole-fused pyridazin-3(2H)-one derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-07-29 | — | — | US | disclosed |
| US-20250066369-A1 | BICYCLIC PHTHALAZIN-1(2H)-ONE DERIVATIVES AND RELATED USES | NodThera Limited (GB) | 2025-02-27 | — | — | US | disclosed |
| EP-4460505-A1 | BICYCLIC PHTHALAZIN-1(2H)-ONE DERIVATIVES AND RELATED USES | Nodthera Limited (GB) | 2024-11-13 | — | — | EP | disclosed |
| CN-118922421-A | Bicyclic phthalazin-1 (2H) -one derivatives and related uses | 诺瑟拉有限公司 | 2024-11-08 | — | — | CN | disclosed |
| EP-4031552-B1 | AZOLE-FUSED PYRIDAZIN-3(2H)-ONE DERIVATIVES | TAKEDA PHARMACEUTICALS CO (JP) | 2024-11-06 | — | — | EP | disclosed |
| WO-2023133271-A1 | BICYCLIC PHTHALAZIN-1(2H)-ONE DERIVATIVES AND RELATED USES | NodThera Limited (GB) | 2023-07-13 | — | — | WO | disclosed |
| US-20230028114-A1 | AZOLE-FUSED PYRIDAZIN-3(2H)-ONE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-01-26 | — | — | US | disclosed |
| US-20230028114-A1 | AZOLE-FUSED PYRIDAZIN-3(2H)-ONE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-01-26 | — | — | US | disclosed |
| EP-4031552-A1 | AZOLE-FUSED PYRIDAZIN-3(2H)-ONE DERIVATIVES | Takeda Pharmaceutical Company Limited (JP) | 2022-07-27 | — | — | EP | disclosed |
| CN-114728975-A | Azole-fused pyridazin-3 (2H) -one derivatives | 武田药品工业株式会社 | 2022-07-08 | — | — | CN | disclosed |
| US-8367282-B2 | Compound or its tautomer, metal complex compound, colored photosensitive curing composition, color filter, and production | FUJIFILM CORPORATION (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8367282-B2 | Compound or its tautomer, metal complex compound, colored photosensitive curing composition, color filter, and production | FUJIFILM CORPORATION (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20120238752-A1 | COMPOUND OR ITS TAUTOMER, METAL COMPLEX COMPOUND, COLORED PHOTOSENSITIVE CURING COMPOSITION, COLOR FILTER, AND PRODUCTION | FUJIFILM CORPORATION (JP) | 2012-09-20 | — | — | US | disclosed |
| US-8197994-B2 | Colorant of a dipyrromethene-based metal complex obtained from a metal of iron, zinc, cobalt, copper or vanadium oxide and a dipyrromethene-based compound and a phthalocyanine dye | FUJIFILM CORPORATION (JP) | 2012-06-12 | — | — | US | disclosed |
| US-20120138877-A1 | COMPOUND OR ITS TAUTOMER, METAL COMPLEX COMPOUND, COLORED PHOTOSENSITIVE CURING COMPOSITION, COLOR FILTER, AND PRODUCTION | FUJIFILM CORPORATION (JP) | 2012-06-07 | — | — | US | disclosed |
| US-20100230647-A1 | COMPOUND OR ITS TAUTOMER, METAL COMPLEX COMPOUND, COLORED PHOTOSENSITIVE CURING COMPOSITION, COLOR FILTER, AND PRODUCTION | FUJIFILM CORPORATION (JP) | 2010-09-16 | — | — | US | disclosed |
| US-20080076044-A1 | Compound or its tautomer, metal complex compound, colored photosensitive curing composition, color filter, and production | FUJIFILM CORPORATION (JP) | 2008-03-27 | — | — | US | disclosed |
| US-6004966-A | ANTIISCHEMIC AGENTS; PYRAZOLO(3,4-D)PYRIMIDINDE, PURINE, ANDPTERIDINE DERIVATIVES | BTG INTERNATIONAL LIMITED (GB) | 1999-12-21 | — | — | US | disclosed |
| EP-0796099-A1 | USE OF XANTHINE OXIDASE INHIBITORS AS ANTI-ISCHAEMIC AGENTS | BTG INTERNATIONAL LIMITED (GB) | 1997-09-24 | — | — | EP | disclosed |
| WO-1996017610-A1 | USE OF XANTHINE OXIDASE INHIBITORS AS ANTI-ISCHAEMIC AGENTS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230028114-A1 | AZOLE-FUSED PYRIDAZIN-3(2H)-ONE DERIVATIVES | GPR139, GPR119, GPR39 | APOBEC3A 4848/4885APOBEC3G 4737/4885ALDH1A1 1955/4885 |
| US-20250066369-A1 | BICYCLIC PHTHALAZIN-1(2H)-ONE DERIVATIVES AND RELATED USES | IL1B, NLRP3, IL1A | APOBEC3A 4137/4885APOBEC3G 4313/4885ALDH1A1 401/4885 |
| US-20120238752-A1 | COMPOUND OR ITS TAUTOMER, METAL COMPLEX COMPOUND, COLORED PHOTOSENSITIVE CURING COMPOSITION, COLOR FILTER, AND PRODUCTION | PBRM1, CRY1, MAPT | APOBEC3A 2435/4885APOBEC3G 3142/4885ALDH1A1 1098/4885 |
| US-12370192-B2 | Azole-fused pyridazin-3(2H)-one derivatives | GPR139, GPR119, GPR39 | APOBEC3A 4848/4885APOBEC3G 4737/4885ALDH1A1 1955/4885 |
| US-20100230647-A1 | COMPOUND OR ITS TAUTOMER, METAL COMPLEX COMPOUND, COLORED PHOTOSENSITIVE CURING COMPOSITION, COLOR FILTER, AND PRODUCTION | CRY1, IK, PRMT5 | APOBEC3A 2311/4885APOBEC3G 3002/4885ALDH1A1 2769/4885 |
| US-20080076044-A1 | Compound or its tautomer, metal complex compound, colored photosensitive curing composition, color filter, and production | PBRM1, CRY1, MAPT | APOBEC3A 2435/4885APOBEC3G 3142/4885ALDH1A1 1098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.