SCHEMBL839994

SCHEMBL839994

Cc1cc(C)cc(-c2[c]c(-c3cc(C)cc(C)c3)ccc2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.46
RXRA P19793 1/20 0.34
RXRB P28702 1/20 0.34
ALDH1A1 P00352 4/20 0.33
TSHR P16473 2/20 0.33
RAB9A P51151 3/20 0.32
BRD9 Q9H8M2 1/20 0.32
BRD7 Q9NPI1 1/20 0.32
MAPK1 P28482 1/20 0.32
NPC1 O15118 2/20 0.32
HPGD P15428 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
TP53 P04637 1/20 0.32
POLB P06746 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ENPP3 O14638 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32
THRB P10828 1/20 0.31
CA1 P00915 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21801276 0.91 ACHE (0.39) ACHERXRARXRBALDH1A1RAB9A
SCHEMBL3824145 0.78 CCR1 (0.42) ADORA2AADORA1
SCHEMBL2774036 0.77 ACHE (0.42) ACHEALDH1A1TSHRRAB9ANPC1
SCHEMBL6310961 0.73 ACHE (0.38) ACHESMN1; SMN2
SCHEMBL2102041 0.73 CYP2A6 (0.38) ACHEALDH1A1TSHRBRD9BRD7
SCHEMBL29628933 0.70 ACHE (0.53) ACHERXRARXRBALDH1A1TSHR
SCHEMBL7914615 0.70 LMNA (0.41) ACHEALDH1A1TSHRRAB9ANPC1
SCHEMBL27885932 0.70 ALDH1A1 (0.33) RXRARXRBALDH1A1TSHR
SCHEMBL21248610 0.70 RXRB (0.44) ACHERXRARXRBALDH1A1HPGD
SCHEMBL9419197 0.69 ACHE (0.67) ACHEALDH1A1TSHRRAB9AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3569606-B1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO (1,2-F)PHENANTHRIDINE AND DIIMIDAZO (1,2-A; 1', 2'-C)QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF UNIVERSAL DISPLAY CORP (US) 2022-01-05 EP claimed
US-10978649-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-04-13 US claimed
US-20200350504-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-11-05 US claimed
US-10749121-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-08-18 US claimed
EP-3569606-A1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO (1,2-F)PHENANTHRIDINE AND DIIMIDAZO (1,2-A; 1', 2'-C)QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF Universal Display Corporation (US) 2019-11-20 EP claimed
US-20190341563-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-11-07 US claimed
US-10403831-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-09-03 US claimed
US-10403832-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2019-09-03 US claimed
US-10381579-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-13 US claimed
EP-2399922-B1 Metal complexes of cyclometallated imidazo(1,2-f) phenanthridine and diimidazo(1,2-A;1',2'-C)quinazoline ligands and isoelectronic and benzannulated analogs therof UNIVERSAL DISPLAY CORP (US) 2019-06-26 EP claimed
US-20130310561-A1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO (1,2-f ) PHENANTHRIDINE AND DIIMIDAZO (1,2-a:1', 2'-c),QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF UNIVERSAL DISPLAY CORPORATION (US) 2013-11-21 US claimed
CN-101490094-B High temperature polyethylene solution polymerization process DOW GLOBAL TECHNOLOGIES INC 2013-06-26 CN claimed
EP-2399922-A1 Metal complexes of cyclometallated imidazo(1,2-f) phenanthridine and diimidazo(1,2-A;1',2'-C)quinazoline ligands and isoelectronic and benzannulated analogs therof Universal Display Corporation (US) 2011-12-28 EP claimed
US-20110073849-A1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO[1,2-f ]PHENANTHRIDINE AND DIIMIDAZO[1,2-a:1',2'-c ]QUNIAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF KNOWLES DAVID B 2011-03-31 US claimed
US-7915415-B2 Metal complexes of cyclometallated imidazo[1,2-f]phenanthridine and diimidazo[1,2-a:1′,2′-c]quinazoline ligands and isoelectronic and benzannulated analogs thereof UNIVERSAL DISPLAY CORPORATION (US) 2011-03-29 US claimed
EP-1878053-B1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORP (US) 2009-08-26 EP claimed
EP-1981898-A2 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZOÝ1,2-f¨PHENANTHRIDINE AND DIIMIDAZOÝ1,2-A:1',2'-C¨QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF Universal Display Corporation (US) 2008-10-22 EP claimed
WO-2007095118-A2 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO[1,2-f]PHENANTHRIDINE AND DIIMIDAZO[1,2-A:1',2'-C]QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF UNIVERSAL DISPLAY CORPORATION (US) 2007-08-23 WO claimed
US-20070190359-A1 Metal complexes of cyclometallated imidazo[1,2-ƒ]phenanthridine and diimidazo[1,2-a:1',2'-c]quinazoline ligands and isoelectronic and benzannulated analogs thereof UNIVERSAL DISPLAY CORPORATION 2007-08-16 US claimed
US-20040171774-A1 Polymerization-active transition metal complexes having bulky ligand systems RIEGER BERNHARD (DE) 2004-09-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110073849-A1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO[1,2-f ]PHENANTHRIDINE AND DIIMIDAZO[1,2-a:1',2'-c ]QUNIAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF NDUFC1, CD274, CRY1 ACHE 649/4885RXRA 777/4885RXRB 1825/4885
US-20190341563-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIG1, L1CAM, LIG3 ACHE 914/4885RXRA 2393/4885RXRB 3647/4885
US-10381579-B2 Stability OLED materials and devices OCIAD2, OCIAD1, OSBP2 ACHE 1764/4885RXRA 2179/4885RXRB 2348/4885
US-10978649-B2 Organic electroluminescent materials and devices NR2C2, NR2E3, NCOA2 ACHE 4215/4885RXRA 365/4885RXRB 348/4885
US-10403832-B2 Organic electroluminescence device LAGE3, L1CAM, LEF1 ACHE 495/4885RXRA 3933/4885RXRB 4177/4885
US-10749121-B2 Organic electroluminescent materials and devices LIG1, L1CAM, LIG3 ACHE 914/4885RXRA 2393/4885RXRB 3647/4885
US-10403831-B2 Organic electroluminescent materials and devices LIG1, L1CAM, LIG3 ACHE 914/4885RXRA 2393/4885RXRB 3647/4885
US-20040171774-A1 Polymerization-active transition metal complexes having bulky ligand systems AP1M1, CCNC, CLTB ACHE 4396/4885RXRA 1222/4885RXRB 774/4885
US-20200350504-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NR2C2, NR2E3, NCOA2 ACHE 4215/4885RXRA 365/4885RXRB 348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.